SynthesisBMC medical research methodology2024
Utilization of EHRs for clinical trials: a systematic review.
Synthesis in BMC medical research methodology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Leveraging Data Science for Conducting Observational Studies: Highlighting Advantages and Limitations Throughout the Evaluation of a Use Case.Mayo Clinic proceedings. Digital health · 2026Article
- CMC-ID: identifying children and youth with medical complexity using an electronic health record.BMJ health & care informatics · 2026Article
- Lessons Learned in Clinical Trial Recruitment: A Partnership Between a Genomic Research Study and the Discover Together Biobank.Biopreservation and biobanking · 2026Review
- Empowering clinical trial design with agentic intelligence and real-world data.Nature communications · 2026Article
- Systematic identification of rare disease patients in electronic health records enables evaluation of clinical outcomes.Scientific reports · 2026Article
- Leveraging structured EMR data for efficient patient prescreening: a practical approach to reducing screen-failure rates in Light Touch Trial.Eye (London, England) · 2026Article
- Real World Evidence Versus Randomised Controlled Trials: Is the Future of Nutritional Sciences Research in Electronic Health Records?Nutrition bulletin · 2026Review
- Advancing Clinical Trial Efficiency and Data Accuracy through Direct EHR-to-EDC Integration.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026Article
- Regional Electronic Health Records in Denmark: Research Potential for Clinical Epidemiology.Clinical epidemiology · 2026Review
- Data science for pediatric infectious disease: utilizing COVID-19 as a model.Current opinion in infectious diseases · 2025Review
- Development and implementation of cancer clinical trial patient screening using an electronic medical record-integrated trial matching system.BMJ health & care informatics · 2025Article
- Article
- "The Truth Is, We Must Miss Some": A Qualitative Study of the Patient Eligibility Screening Process, and Automation Perspectives, for Cancer Clinical Trials.Cancer medicine · 2024Article
- A Framework for the Use and Likelihood of Regulatory Acceptance of Single-Arm Trials.Therapeutic innovation & regulatory science · 2024Review
- Lipid-Lowering Treatment Gaps in Patients after Acute Myocardial Infarction: Using Global Database TriNetX.Medicina (Kaunas, Lithuania) · 2024Article
- Recommending Clinical Trials for Online Patient Cases using Artificial Intelligence.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveClinical trials are of high importance for medical progress. This study conducted a systematic review to identify the applications of EHRs in supporting and enhancing clinical trials. MATERIALS AND
methodsA systematic search of PubMed was conducted on 12/3/2023 to identify relevant studies on the use of EHRs in clinical trials. Studies were included if they (1) were full-text journal articles, (2) were written in English, (3) examined applications of EHR data to support clinical trial processes (e.g. recruitment, screening, data collection). A standardized form was used by two reviewers to extract data on: study design, EHR-enabled process(es), related outcomes, and limitations.
resultsFollowing full-text review, 19 studies met the predefined eligibility criteria and were included. Overall, included studies consistently demonstrated that EHR data integration improves clinical trial feasibility and efficiency in recruitment, screening, data collection, and trial design.
conclusionsAccording to the results of the present study, the use of Electronic Health Records in conducting clinical trials is very helpful. Therefore, it is better for researchers to use EHR in their studies for easy access to more accurate and comprehensive data. EHRs collects all individual data, including demographic, clinical, diagnostic, and therapeutic data. Moreover, all data is available seamlessly in EHR. In future studies, it is better to consider the cost-effectiveness of using EHR in clinical trials.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.