Evidence map›Paper›PMID 38495122›Full record

ReviewMedComm2024

Alterations in microbiota of patients with COVID-19: implications for therapeutic interventions.

Yong Qiu, Chunheng Mo, Lu Chen, Wanlin Ye, Guo Chen, Tao Zhu

Open access · goldAbstract readReview
In one paragraph

Review in MedComm, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Microbiome and Long COVID-19: Current Evidence and Insights.International journal of molecular sciences · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yong QiuDepartment of Anesthesiology National Clinical Research Center for Geriatrics and The Research Units of West China (2018RU012) West China Hospital Sichuan University Chengdu China.
Chunheng MoKey Laboratory of Birth Defects and Related Diseases of Women and Children of MOE State Key Laboratory of Biotherapy West China Second University Hospital Sichuan University Chengdu China.ORCID https://orcid.org/0000-0003-2781-2132
Lu ChenDepartment of Anesthesiology National Clinical Research Center for Geriatrics and The Research Units of West China (2018RU012) West China Hospital Sichuan University Chengdu China.
Wanlin YeDepartment of Anesthesiology National Clinical Research Center for Geriatrics and The Research Units of West China (2018RU012) West China Hospital Sichuan University Chengdu China.
Guo ChenDepartment of Anesthesiology National Clinical Research Center for Geriatrics and The Research Units of West China (2018RU012) West China Hospital Sichuan University Chengdu China.
Tao ZhuDepartment of Anesthesiology National Clinical Research Center for Geriatrics and The Research Units of West China (2018RU012) West China Hospital Sichuan University Chengdu China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recently caused a global pandemic, resulting in more than 702 million people being infected and over 6.9 million deaths. Patients with coronavirus disease (COVID-19) may suffer from diarrhea, sleep disorders, depression, and even cognitive impairment, which is associated with long COVID during recovery. However, there remains no consensus on effective treatment methods. Studies have found that patients with COVID-19 have alterations in microbiota and their metabolites, particularly in the gut, which may be involved in the regulation of immune responses. Consumption of probiotics may alleviate the discomfort caused by inflammation and oxidative stress. However, the pathophysiological process underlying the alleviation of COVID-19-related symptoms and complications by targeting the microbiota remains unclear. In the current study, we summarize the latest research and evidence on the COVID-19 pandemic, together with symptoms of SARS-CoV-2 and vaccine use, with a focus on the relationship between microbiota alterations and COVID-19-related symptoms and vaccine use. This work provides evidence that probiotic-based interventions may improve COVID-19 symptoms by regulating gut microbiota and systemic immunity. Probiotics may also be used as adjuvants to improve vaccine efficacy.

Indexed as

COVID‐19gut microbiotaimmunityprobioticsvaccine

Identifiers

PMID38495122
PMCPMC10943180
OpenAlexW4392882812

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.