Evidence map›Paper›PMID 38496567›Full record

ArticleResearch square2024

Brain dynamics reflecting an intra-network brain state is associated with increased posttraumatic stress symptoms in the early aftermath of trauma.

Mohammad Sendi, Zening Fu, Nathaniel Harnett, Sanne van Rooij, Victor Vergara, Diego Pizzagalli, Nikolaos Daskalakis, Stacey House, Francesca Beaudoin, Xinming An and 40 more

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

50 authors at 20 institutions in 1 country.

Mohammad SendiHarvard Medical School/McLean Hospital.
Zening Fud Data Science (TReNDS), Georgia State University, Georgia Institute of Technology, Emory University.
Nathaniel HarnettMcLean Hospital.ORCID 0000-0001-5346-2012
Sanne van RooijEmory University School of Medicine.ORCID 0000-0002-0160-7248
Victor VergaraBlue Halo.
Diego PizzagalliHarvard Medical School/McLean Hospital.ORCID 0000-0002-7772-1143
Nikolaos DaskalakisMcLean Hospital, Harvard Medical School.ORCID 0000-0003-1660-9112
Stacey HouseWashington University School of Medicine.
Francesca BeaudoinThe Alpert Medical School of Brown University, Rhode Island Hospital and The Miriam Hospital.
Xinming AnUniversity of North Carolina at Chapel Hill.
Thomas NeylanSan Francisco VA Healthcare System; University of California San Francisco.ORCID 0000-0002-1572-2626
Gari CliffordEmory University School of Medicine; Georgia Institute of Technology.
Tanja JovanovicWayne State University School of Medicine.
Sarah LinnstaedtUniversity of North Carolina at Chapel Hill.ORCID 0000-0001-5295-7072
Laura GermineMcLean Hospital.ORCID 0000-0001-8690-8412
Kenneth BollenUniversity of North Carolina Chapel Hill.
Scott RauchMcLean Hospital.
John HaranUniversity of Massachusetts Medical School.ORCID 0000-0001-7311-1121
Alan StorrowVanderbilt University Medical Center.ORCID 0000-0002-2893-808X
Christopher LewandowskiORCID 0000-0001-8297-0024
Paul MuseyIndiana University School of Medicine.ORCID 0000-0002-5693-190X
Phyllis HendryUniversity of Florida College of Medicine -Jacksonville.
Christopher JonesCooper Medical School of Rowan University.
Brittany PunchesUniversity of Cincinnati College of Medicine & University of Cincinnati College of Nursing.ORCID 0000-0002-7546-1966
Robert SworBeaumont Hospital.
Nina GentileTemple University.
Vishnu MurtyTemple University.
Lauren HudakEmory University School of Medicine.
Jose PascualPerelman School of Medicine at the University of Pennsylvania.ORCID 0000-0002-1613-7912
Mark SeamonUniversity of Pennsylvania.
Erica HarrisEinstein Medical Center.
Anna ChangJefferson University Hospitals.
Claire PearsonWayne State University; Ascension St. John Hospital.
David PeakMassachusetts General Hospital.
Roland MerchantBrigham and Women's Hospital.
Robert DomeierSaint Joseph Mercy Hospital.
Niels RathlevUniversity of Massachusetts Medical School-Baystate.
Brian O'NeilWayne State University School of Medicine.
Paulina SergotDepartment of Emergency Medicine, McGovern Medical School at UTHealth.
Leon SanchezBrigham and Women's Hospital.ORCID 0000-0002-8807-0913
Steven BruceUniversity of Missouri-St. Louis.ORCID 0000-0002-5807-4382
John SheridanOhio State University College of Dentistry.
Steven HarteUniversity of Michigan.
Ronald KesslerHarvard Medical School.ORCID 0000-0003-4831-2305
Karestan KoenenHarvard School of Public Health.ORCID 0000-0003-2978-7655
Samuel McLeanUniversity of North Carolina.ORCID 0000-0001-9482-3582
Jennifer StevensEmory University School of Medicine.ORCID 0000-0003-4674-0314
Vince CalhounGeorgia Institute of Technology, Emory University and Georgia State University.ORCID 0000-0001-9058-0747
Kerry ResslerMcLean Hospital.ORCID 0000-0002-5158-1103
Harvard University · USMcLean Hospital · USEmory University · USGeorgia Institute of Technology · USUniversity of North Carolina at Chapel Hill · USWayne State University · USBrigham and Women's Hospital · USTemple College · USUniversity of Massachusetts Chan Medical School · USBotsford Hospital · USBrown University · USCalifornia University of Pennsylvania · USCooper Medical School of Rowan University · USEinstein Medical Center Philadelphia · USJefferson University Hospitals · USMassachusetts General Hospital · USThe Ohio State University · USThe University of Texas Health Science Center at Houston · USTrinity Health Michigan · USUniversity of California, San Francisco · US

Funding

Longitudinal Assessment of Post-traumatic SyndromesU01MH110925 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KESSLER, RONALD C, KOENEN, KARESTAN C · 2016 to 2020
$25.8M
Extracellular vesicles as biomarkers of trauma exposure and PTSD riskR01MH129495 · NIMH · UNIVERSITY OF COLORADO DENVER · PI Tracy L Bale, Tanja Jovanovic · 2022 to 2026
$4.0M
Mobile Measures of Threat Sensitivity for Cross-sectional and Longitudinal AssessmentR01MH121617 · NIMH · MCLEAN HOSPITAL · PI GERMINE, LAURA THI · 2020 to 2025
$3.9M
Facilitation of Extinction Retention and Reconsolidation Blockade by IV Allopregnanolone in PTSDR01MH122867 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI ANN M. RASMUSSON · 2020 to 2026
$3.6M
Data-driven solutions for temporal, spatial, and spatiotemporal dynamic functional connectivityR01MH123610 · NIMH · GEORGIA STATE UNIVERSITY · PI ADALI, TULAY, CALHOUN, VINCE D · 2021 to 2025
$3.1M
Training to Enhance Alignment of Psychiatry and NeuroscienceT32MH125786 · NIMH · MCLEAN HOSPITAL · PI William A. Carlezon, KERRY J. RESSLER · 2021 to 2026
$2.0M
Effect of TMS on PTSD Neuroimaging and Psychophysiological BiomarkersK01MH121653 · NIMH · EMORY UNIVERSITY · PI VAN ROOIJ, SANNE JH · 2020 to 2024
$894k
Multimodal characterization of affective visual processing in the early aftermath of traumaK01MH129828 · NIMH · MCLEAN HOSPITAL · PI Nathaniel G Harnett · 2023 to 2026
$719k
NIMH NIH HHS K01 MH121653NIMH NIH HHS K01 MH129828NIMH NIH HHS R01 MH121617NIMH NIH HHS R01 MH122867NIMH NIH HHS R01 MH123610NIMH NIH HHS R01 MH129495NIMH NIH HHS T32 MH125786NIMH NIH HHS U01 MH110925
6 · The paper itself

Abstract

This study examines the association between brain dynamic functional network connectivity (dFNC) and current/future posttraumatic stress (PTS) symptom severity, and the impact of sex on this relationship. By analyzing 275 participants' dFNC data obtained ~2 weeks after trauma exposure, we noted that brain dynamics of an inter-network brain state link negatively with current (r=-0.179,

Identifiers

PMID38496567
PMCPMC10942549
OpenAlexW4392581919

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.