Evidence map›Paper›PMID 38497616›Full record

ArticleAntimicrobial agents and chemotherapy2024

Promising aryl selenoate derivatives as antileishmanial agents and their effects on gene expression.

Celia Fernández-Rubio, Mercedes Rubio-Hernández, Verónica Alcolea, Aroia Burguete-Mikeo, Paul A Nguewa, Silvia Pérez-Silanes

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Celia Fernández-RubioISTUN Institute of Tropical Health, Department of Microbiology and Parasitology, Universidad de Navarra, IdiSNA (Navarra Institute for Health Research), Navarra, Spain.
Mercedes Rubio-HernándezISTUN Institute of Tropical Health, Department of Pharmaceutical Sciences, Universidad de Navarra, IdiSNA (Navarra Institute for Health Research), Pamplona, Spain.ORCID 0000-0002-7375-4335
Verónica AlcoleaISTUN Institute of Tropical Health, Department of Pharmaceutical Sciences, Universidad de Navarra, IdiSNA (Navarra Institute for Health Research), Pamplona, Spain.
Aroia Burguete-MikeoISTUN Institute of Tropical Health, Department of Microbiology and Parasitology, Universidad de Navarra, IdiSNA (Navarra Institute for Health Research), Navarra, Spain.
Paul A NguewaISTUN Institute of Tropical Health, Department of Microbiology and Parasitology, Universidad de Navarra, IdiSNA (Navarra Institute for Health Research), Navarra, Spain.
Silvia Pérez-SilanesISTUN Institute of Tropical Health, Department of Pharmaceutical Sciences, Universidad de Navarra, IdiSNA (Navarra Institute for Health Research), Pamplona, Spain.ORCID 0000-0002-6284-4546
Navarre Institute of Health Research · ES

Funding

Fundación La Caixa LCF/PR/PR13/51080005Fundación Roviralta and UbesolSpanish Ministry of Science and Innovation PID2020-112713RB-C21Spanish Ministry of Universities FPU21/04585
6 · The paper itself

Abstract

Leishmaniasis remains one of the main public health problems worldwide, with special incidence in the poorest populations. Selenium and its derivatives can be potent therapeutic options against protozoan parasites. In this work, 17 aryl selenoates were synthesized and screened against three species of

Indexed as

Antiprotozoal AgentsLeishmania infantumLeishmania mexicanaLeishmaniasisAnimalsGene ExpressionHumansMiceMice, Inbred BALB CAntiprotozoal Agentsantileishmanial agentsaryl selenoatesLeishmania spp.selenium

Identifiers

PMID38497616
PMCPMC10994822
OpenAlexW4392913018

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.