Evidence map›Paper›PMID 38498092›Full record

ArticleNeuroscience bulletin2024

L-Type Calcium Channel Modulates Low-Intensity Pulsed Ultrasound-Induced Excitation in Cultured Hippocampal Neurons.

Wen-Yong Fan, Yi-Ming Chen, Yi-Fan Wang, Yu-Qi Wang, Jia-Qi Hu, Wen-Xu Tang, Yi Feng, Qian Cheng, Lei Xue

Open access · greenAbstract read
In one paragraph

Article in Neuroscience bulletin, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Wen-Yong FanState Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.
Yi-Ming ChenInstitute of Acoustics, School of Physics Science and Engineering, Tongji University, Shanghai, 200092, China.
Yi-Fan WangInstitute of Acoustics, School of Physics Science and Engineering, Tongji University, Shanghai, 200092, China.
Yu-Qi WangState Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.
Jia-Qi HuState Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.
Wen-Xu TangState Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China.
Yi FengDepartment of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China.
Qian ChengInstitute of Acoustics, School of Physics Science and Engineering, Tongji University, Shanghai, 200092, China. q.cheng@tongji.edu.cn.
Lei XueState Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, 200433, China. lxue@fudan.edu.cn.
Fudan University · CNInstitute of Acoustics · CNHangzhou Medical College · CNShanghai First People's Hospital · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a noninvasive technique, ultrasound stimulation is known to modulate neuronal activity both in vitro and in vivo. The latest explanation of this phenomenon is that the acoustic wave can activate the ion channels and further impact the electrophysiological properties of targeted neurons. However, the underlying mechanism of low-intensity pulsed ultrasound (LIPUS)-induced neuro-modulation effects is still unclear. Here, we characterize the excitatory effects of LIPUS on spontaneous activity and the intracellular Ca

Indexed as

CalciumCalcium Channels, L-TypeHippocampusNeuronsUltrasonic WavesAction PotentialsAnimalsCells, CulturedExcitatory Postsynaptic PotentialsPatch-Clamp TechniquesRatsRats, Sprague-DawleyCalciumCalcium Channels, L-TypeHippocampal neuronLow-intensity pulsed ultrasoundL-type calcium channelNeuromodulation

Identifiers

PMID38498092
PMCPMC11250733
OpenAlexW4392916511

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.