Evidence map›Paper›PMID 38498243›Full record

SynthesisGlycoconjugate journal2024

Associations of circulating advanced glycation end products and their soluble receptors with cancer risk: A systematic review and meta-analysis of observational studies.

Fatemeh Hajizadeh-Sharafabad, Sara Shojaei-Zarghani, Elham Sharifi-Zahabi, Farzad Gerami, Mohammad Reza Pashaei

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Glycoconjugate journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Fatemeh Hajizadeh-SharafabadPatient Safety Research Center, Clinical Research Institute, Urmia University of Medical Sciences, Urmia, Iran.
Sara Shojaei-ZarghaniColorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Elham Sharifi-ZahabiStudent Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Farzad GeramiPatient Safety Research Center, Clinical Research Institute, Urmia University of Medical Sciences, Urmia, Iran.
Mohammad Reza PashaeiPatient Safety Research Center, Clinical Research Institute, Urmia University of Medical Sciences, Urmia, Iran. dr.pashaei@yahoo.com.
Urmia University of Medical SciencesKermanshah University of Medical Sciences · IRShiraz University of Medical Sciences · IRUrmia University · IR

Funding

Urmia University of Medical Sciences 12420
6 · The paper itself

Abstract

Advanced glycation end products (AGE) in complex with their receptors (RAGE) cause a chronic inflammatory state in the body, which is the major mechanism in cancer development. This study aimed to conduct a systematic review and meta-analysis on the observational studies investigating the association between AGEs / sRAGE and cancer incidence. The PubMed, Scopus, and Web of Science databases were comprehensively searched to identify papers focused on the associations of sRAGE and AGEs with cancer incidence up to May 2023. Eight studies with a total of 7690 participants were included in the analysis to evaluate the association between circulating sRAGE and cancer incidence. The results indicated that circulating sRAGE (per 100 ng/L) had a significant inverse association with cancer incidence (RR 0.977; 95% CI 0.956, 0.999; p = 0.036; I

Indexed as

Glycation End Products, AdvancedNeoplasmsBiomarkersHumansInflammationObservational Studies as TopicReceptor for Advanced Glycation End ProductsBiomarkersGlycation End Products, AdvancedReceptor for Advanced Glycation End ProductsAdvanced glycation end productsSoluble receptor for advanced glycation end

Identifiers

PMID38498243
OpenAlexW4392922970

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.