Evidence map›Paper›PMID 38498428›Full record

ArticlePloS one2024

Factors associated with COVID-19 among hospitalized patients with severe acute respiratory infections in Serbia, 2022-2023: A test negative case-control study.

Maja Stosic, Dragana Plavsa, Verica Jovanovic, Marko Veljkovic, Dragan Babic, Aleksandra Knezevic, Vladan Saponjic, Dragana Dimitrijevic, Miljan Rancic, Marija Milic and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Maja StosicInstitute of Public Health of Serbia "Dr Milan Jovanovic Batut", Belgrade, Serbia.ORCID 0000-0003-0478-1716
Dragana PlavsaInstitute of Public Health of Serbia "Dr Milan Jovanovic Batut", Belgrade, Serbia.
Verica JovanovicInstitute of Public Health of Serbia "Dr Milan Jovanovic Batut", Belgrade, Serbia.
Marko VeljkovicInstitute of Public Health of Serbia "Dr Milan Jovanovic Batut", Belgrade, Serbia.
Dragan BabicInstitute of Public Health of Serbia "Dr Milan Jovanovic Batut", Belgrade, Serbia.
Aleksandra KnezevicInstitute for Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.ORCID 0000-0003-3451-810X
Vladan SaponjicInstitute of Public Health of Serbia "Dr Milan Jovanovic Batut", Belgrade, Serbia.
Dragana DimitrijevicInstitute of Public Health of Serbia "Dr Milan Jovanovic Batut", Belgrade, Serbia.
Miljan RancicWorld Health Organization, Country Office Serbia, Belgrade, Serbia.
Marija MilicInstitute of Public Health of Serbia "Dr Milan Jovanovic Batut", Belgrade, Serbia.
Tatjana Adzic-VukicevicCOVID Hospital "Batajnica", University Clinical Centre of Serbia, Belgrade, Serbia.
Institute of Public Health of Serbia · RSCenter for Health, Exercise and Sport Sciences · RSUniversity of Belgrade · RS

Funding

World Health Organization 001
6 · The paper itself

Abstract

Severe acute respiratory infections (SARI) are estimated to be the cause of death in about 19% of all children younger than 5 years globally. The outbreak of coronaviral disease (COVID-19) caused by SARS-CoV-2, increased considerably the burden of SARI worldwide. We used data from a vaccine effectiveness study to identify the factors associated with SARS CoV-2 infection among hospitalized SARI patients. We recruited SARI patients at 3 hospitals in Serbia from 7 April 2022-1 May 2023. We collected demographic and clinical data from patients using a structured questionnaire, and all SARI patients were tested for SARS-CoV-2 by RT-PCR. We conducted an unmatched test negative case-control study. SARS-CoV-2 infected SARI patients were considered cases, while SARS CoV-2 negative SARI patients were controls. We conducted bivariate and multivariable logistic regression analysis in order to identify variables associated with SARS-CoV-2 infection. We included 110 SARI patients: 74 were cases and 36 controls. We identified 5 factors associated with SARS-CoV-2 positivity, age (OR  =  1.04; 95% CI  =  1.01-1.07), having received primary COVID-19 vaccine series (OR  =  0.28; 95% CI  =  0.09-0.88), current smoking (OR  =  8.64; 95% CI  =  2.43-30.72), previous SARS CoV-2 infection (OR  =  3.48; 95% CI  =  1.50-8.11) and number of days before seeking medical help (OR  =  0.81; 95% CI  =  0.64-1.02). In Serbia during a period of Omicron circulation, we found that older age, unvaccinated, hospitalized SARI patients, previously infected with SARS CoV-2 virus and those who smoked, were more likely to be SARS-CoV-2-positive; these patient populations should be prioritized for COVID vaccination.

Indexed as

COVID-19PneumoniaCase-Control StudiesChildCOVID-19 VaccinesHumansSARS-CoV-2SerbiaCOVID-19 Vaccines

Identifiers

PMID38498428
PMCPMC10947665
OpenAlexW4392914736

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.