Evidence map›Paper›PMID 38499325›Full record

GuidelineAnnals of the rheumatic diseases2024

EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2023 update.

Laure Gossec, Andreas Kerschbaumer, Ricardo J O Ferreira, Daniel Aletaha, Xenofon Baraliakos, Heidi Bertheussen, Wolf-Henning Boehncke, Bente Appel Esbensen, Iain B McInnes, Dennis McGonagle and 26 more

Open access · hybridAbstract readPractice GuidelineSystematic Review
In one paragraph

Guideline in Annals of the rheumatic diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 214 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
214citing papers in PubMed, 9 pooled it
131.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

214 citing papers in PubMed, 9 syntheses or guidelines pooled it, 283 citations in OpenAlex.

  1. French guidelines on systemic treatments for moderate-to-severe psoriasis in adults: Update 2025.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
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  6. La Tunisie medicale · 2025
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154 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 20 institutions in 17 countries.

Laure GossecINSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Sorbonne Universite, Paris, France laure.gossec@aphp.fr.ORCID http://orcid.org/0000-0002-4528-310X
Andreas KerschbaumerDivision of Rheumatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0002-6685-8873
Ricardo J O FerreiraNursing Research, Innovation and Development Centre of Lisbon (CIDNUR), Higher School of Nursing of Lisbon, Lisbon, Portugal.ORCID http://orcid.org/0000-0002-2517-0247
Daniel AletahaDivision of Rheumatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0003-2108-0030
Xenofon BaraliakosRheumazentrum Ruhrgebiet, Ruhr University Bochum, Herne, Germany.ORCID http://orcid.org/0000-0002-9475-9362
Heidi BertheussenEULAR Patient Research Partner, EULAR, Oslo, Norway.
Wolf-Henning BoehnckeDermatology and Venereology, Geneva University Hospitals, Geneva, Switzerland.
Bente Appel EsbensenCopenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark.ORCID http://orcid.org/0000-0001-5331-8221
Iain B McInnesCollege of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Dennis McGonagleLTHT, NIHR Leeds Biomedical Research Centre, Leeds, UK.
Kevin L WinthropDivision of Infectious Diseases, School of Medicine, School of Public Health, Oregon Health & Science University, Portland, Oregon, USA.ORCID http://orcid.org/0000-0002-3892-6947
Andra BalanescuSf Maria Hospital, University of Medicine and Pharmacy Carol Davila Bucharest, Bucharest, Romania.
Peter V BalintMedical Imaging Centre, Semmelweis University, 3rd Rheumatology Department, National Institute of Musculoskeletal Diseases, Budapest, Hungary.
Gerd R BurmesterDepartment of Rheumatology and Clinical Immunology, Freie Universität Berlin and Humboldt-Universität zu Berlin, Charité Universitätsmedizin Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0001-7518-1131
Juan D CañeteArthritis Unit, Department of Rheumatology, Hospital Clínic Barcelona, Barcelona, Spain.ORCID http://orcid.org/0000-0003-2606-0573
Pascal ClaudepierreRheumatology, AP-HP, Henri Mondor University Hospital, Creteil, France.
Lihi EderDepartment of Medicine, University of Toronto, Women's College Hospital, Toronto, Toronto, Canada.ORCID http://orcid.org/0000-0002-1473-1715
Merete Lund HetlandThe Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre of Head and Orthopedics, Rigshospitalet Glostrup, Glostrup, Denmark.ORCID http://orcid.org/0000-0003-4229-6818
Annamaria IagnoccoAcademic Rheumatology Centre, Dipartimento Scienze Cliniche Biologiche, Università di Torino - AO Mauriziano Torino, Turin, Italy.ORCID http://orcid.org/0000-0001-5592-724X
Lars Erik KristensenThe Parker Institute, Bispebjerg, Denmark.
Rik LoriesLaboratory of Tissue Homeostasis and Disease, Skeletal Biology and Engineering Research Center, KU Leuven, Leuven, Belgium.
Rubén QueiroRheumatology, Hospital Universitario Central de Asturias, Oviedo, Spain.ORCID http://orcid.org/0000-0002-8418-7145
Daniele MauroDepartment of Precision Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.ORCID http://orcid.org/0000-0002-9022-8863
Helena Marzo-OrtegaLTHT, NIHR Leeds Biomedical Research Centre, Leeds, UK.ORCID http://orcid.org/0000-0002-9683-3407
Philip J MeaseRheumatology Research, Providence Swedish, Seattle, Washington, USA.ORCID http://orcid.org/0000-0002-6620-0457
Peter NashSchool of Medicine, Griffith University, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-2571-788X
Wendy WagenaarTranzo, Tilburg School of Social and Behavioral Sciences, Tilburg University, Tilburg, The Netherlands.
Laura SavageSchool of Medicine and Dermatology, Leeds Teaching Hospitals NHS Trust, University of Leeds, Leeds, UK.
Georg SchettDepartment of Internal Medicine 3, Rheumatology and Immunology and Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.ORCID http://orcid.org/0000-0001-8740-9615
Stephanie J W Shoop-WorrallChildren and Young Person's Rheumatology Research Programme, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0002-9441-5535
Yoshiya TanakaFirst Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.ORCID http://orcid.org/0000-0002-0807-7139
Filip E Van den BoschDepartment of Internal Medicine and Pediatrics, VIB Center for Inflammation Research, Ghent University, Gent, Belgium.ORCID http://orcid.org/0000-0002-3561-5932
Annette van der Helm-van MilRheumatology, Leiden University Medical Center, Leiden, The Netherlands.
Alen ZabottiDepartment of Medical and Biological Sciences, Azienda sanitaria universitaria Friuli Centrale, Udine, Italy.ORCID http://orcid.org/0000-0002-0573-464X
Désirée van der HeijdeRheumatology, Leiden University Medical Center, Leiden, The Netherlands.ORCID http://orcid.org/0000-0002-5781-158X
Josef S SmolenDivision of Rheumatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria.
Medical University of Vienna · ATUniversity of Leeds · GBLeiden University Medical Center · NLUniversity of Copenhagen · DKCarol Davila University of Medicine and Pharmacy · ROCharité - Universitätsmedizin Berlin · DEFrederiksberg Hospital · DKFriedrich-Alexander-Universität Erlangen-Nürnberg · DEGhent University · BEGriffith University · AUHospitais da Universidade de Coimbra · PTHospital Clínic de Barcelona · ESHospital Universitario Central de Asturias · ESInserm · FRKU Leuven · BEOregon Health & Science University · USProvidence College · USRheumazentrum Ruhrgebiet · DESemmelweis University · HUTilburg University · NL

Funding

Medical Research Council MR/W027151/1
6 · The paper itself

Abstract

objectiveNew modes of action and more data on the efficacy and safety of existing drugs in psoriatic arthritis (PsA) required an update of the EULAR 2019 recommendations for the pharmacological treatment of PsA.

methodsFollowing EULAR standardised operating procedures, the process included a systematic literature review and a consensus meeting of 36 international experts in April 2023. Levels of evidence and grades of recommendations were determined.

resultsThe updated recommendations comprise 7 overarching principles and 11 recommendations, and provide a treatment strategy for pharmacological therapies. Non-steroidal anti-inflammatory drugs should be used in monotherapy only for mild PsA and in the short term; oral glucocorticoids are not recommended. In patients with peripheral arthritis, rapid initiation of conventional synthetic disease-modifying antirheumatic drugs is recommended and methotrexate preferred. If the treatment target is not achieved with this strategy, a biological disease-modifying antirheumatic drug (bDMARD) should be initiated, without preference among modes of action. Relevant skin psoriasis should orient towards bDMARDs targeting interleukin (IL)-23p40, IL-23p19, IL-17A and IL-17A/F inhibitors. In case of predominant axial or entheseal disease, an algorithm is also proposed. Use of Janus kinase inhibitors is proposed primarily after bDMARD failure, taking relevant risk factors into account, or in case bDMARDs are not an appropriate choice. Inflammatory bowel disease and uveitis, if present, should influence drug choices, with monoclonal tumour necrosis factor inhibitors proposed. Drug switches and tapering in sustained remission are also addressed.

conclusionThese updated recommendations integrate all currently available drugs in a practical and progressive approach, which will be helpful in the pharmacological management of PsA.

Indexed as

Antirheumatic AgentsArthritis, PsoriaticAnti-Inflammatory Agents, Non-SteroidalBiological ProductsHumansMethotrexateAnti-Inflammatory Agents, Non-SteroidalAntirheumatic AgentsBiological ProductsMethotrexateBiological TherapyBiosimilar PharmaceuticalsPsoriatic ArthritisTreatment

Identifiers

PMID38499325
PMCPMC11103320
OpenAlexW4392926454

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.