Observational studyCardiovascular diabetology2024
Postpartum weight retention and the early evolution of cardiovascular risk over the first 5 years after pregnancy.
Observational study in Cardiovascular diabetology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 25 citations in OpenAlex.
- Understanding Postpartum Mothers' Perspectives of Chrononutrition Approaches: A Qualitative Study.Journal of the Academy of Nutrition and Dietetics · 2026Article
- Risk Factors for Postpartum Weight Retention in Postpartum Women: An Integrative Review.Nursing open · 2026Review
- Postpartum weight change one year after delivery and associated factors among women in Puducherry, South India: Findings from the JANMAM cohort.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Optimizing the Postpartum Period to Support Lifelong Health for Women with Obesity.Current obesity reports · 2026Review
- Bridging the Gaps: A Critical Review of National Dietary and Lifestyle Guidelines for Pregnant Women in the Eastern Mediterranean Region.Maternal and child health journal · 2026Review
- Maternal obesity and the metabolic syndrome in reproductive health: assessing incretin-based interventions.Reviews in endocrine & metabolic disorders · 2026Review
- Central Adiposity Indicators by Pre-Pregnancy BMI at the 23 kg/mNursing reports (Pavia, Italy) · 2026Article
- Antenatal glycemic control in gestational diabetes and its association with postpartum glucose intolerance and weight retention.Clinics (Sao Paulo, Brazil) · 2026Article
- Weight Change Between Pregnancies and Mortality Over 50 Years of Follow-Up.Obesity (Silver Spring, Md.) · 2026Article
- Maternal cardiometabolic health and the role of GLP-1 receptor agonists from preconception to postpartum: A review of evidence and opportunities.American journal of preventive cardiology · 2026Review
- Exploring cardiometabolic markers in adverse pregnancy outcomes: insights from the GROWell study.Research square · 2026Article
- Postpartum Body Mass Index Change Is Associated with Incident Dysglycemia in Women with a History of Gestational Diabetes Mellitus: A Prospective Cohort Study.Journal of clinical medicine · 2026Article
- Perceived Risk Perception of Future Cardiovascular Disease and Diabetes in the Postpartum Period.Journal of personalized medicine · 2026Article
- The Impact of Metabolic Complications in Pregnancy on Later Life Maternal Cardiometabolic Health: Findings From the ROLO Longitudinal Cohort Study.BJOG : an international journal of obstetrics and gynaecology · 2026Article
- Pharmacological Management of Obesity in Pregnancy: A Review of Current and Emerging Therapies.Drugs · 2026Review
- The Association of Physical Activity During Pregnancy and Postpartum Weight Retention: A Retrospective Cohort Study.Obesity (Silver Spring, Md.) · 2026Article
- Maternal Prepregnancy Overweight: Associations With Maternal and Offspring Weight 4-7 Years Postpartum.Journal of diabetes research · 2026Article
- Weight management in women of reproductive age.Obesity and endocrinology · 2026Review
- Pre-pregnancy BMI modifies the optimal interpregnancy interval for preventing preterm birth: a population-based retrospective cohort study.Frontiers in endocrinology · 2026Article
- A Smartphone App (PRIMI) to Promote Healthy Diet, Physical Activity, and Health Literacy After Childbirth Among Migrant Women: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2025Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe cumulative effect of postpartum weight retention from each pregnancy in a woman's life may contribute to her risk of ultimately developing type 2 diabetes and cardiovascular disease. However, there is limited direct evidence supporting this hypothesis. Thus, we sought to characterize the impact of postpartum weight retention on the trajectories of cardiovascular risk factors over the first 5-years after pregnancy.
methodsIn this prospective observational cohort study, 330 women (mean age 35.7 ± 4.3 years, mean pre-pregnancy body mass index 25.2 ± 4.8 kg/m
resultsAt 1-year postpartum, cardiovascular risk factors did not differ between the groups. However, an adverse risk factor profile progressively emerged in the weight retention groups at 3- and 5-years. Indeed, after covariate adjustment, there was stepwise worsening (from the weight loss group to weight gain 0-6% to weight gain ≥ 6% group) of the following cardiovascular risk factors at 5-years: triglycerides (p = 0.001), HDL (p = 0.02), LDL (p = 0.01), apolipoprotein-B (p = 0.003), Matsuda index (p < 0.0001), HOMA-IR (p < 0.0001), fasting glucose (p = 0.07), and CRP (p = 0.01). Moreover, on logistic regression analyses, weight gain ≥ 6% emerged as an independent predictor of pre-diabetes/diabetes at 5-years (adjusted OR = 3.40, 95%CI: 1.63-7.09).
conclusionPostpartum weight retention predicts trajectories of worsening cardiovascular risk factors and glucose intolerance over the first 5-years after delivery, consistent with its postulated contribution to future vascular disease in women.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.