Evidence map›Paper›PMID 38501901›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Layered Double Hydroxides: Recent Progress and Promising Perspectives Toward Biomedical Applications.

Lei Li, Irem Soyhan, Eliza Warszawik, Patrick van Rijn

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Review
  2. Nanostructured Ion Conductor Design for Highly Efficient Ion Transport.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  3. Review
  4. Article
  5. CaMaterials today. Bio · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Advanced Therapeutic Approach Based on LDHs-Mimetic Oxidoreductase.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lei LiDepartment of Biomedical Engineering, University of Groningen, University Medical Center Groningen, A. Deusinglaan 1, Groningen, AV, 9713, The Netherlands.
Irem SoyhanDepartment of Biomedical Engineering, University of Groningen, University Medical Center Groningen, A. Deusinglaan 1, Groningen, AV, 9713, The Netherlands.
Eliza WarszawikDepartment of Biomedical Engineering, University of Groningen, University Medical Center Groningen, A. Deusinglaan 1, Groningen, AV, 9713, The Netherlands.
Patrick van RijnDepartment of Biomedical Engineering, University of Groningen, University Medical Center Groningen, A. Deusinglaan 1, Groningen, AV, 9713, The Netherlands.ORCID 0000-0002-2208-5725

Funding

China Scholarship Council 201906020178
6 · The paper itself

Abstract

Layered double hydroxides (LDHs) have been widely studied for biomedical applications due to their excellent properties, such as good biocompatibility, degradability, interlayer ion exchangeability, high loading capacity, pH-responsive release, and large specific surface area. Furthermore, the flexibility in the structural composition and ease of surface modification of LDHs makes it possible to develop specifically functionalized LDHs to meet the needs of different applications. In this review, the recent advances of LDHs for biomedical applications, which include LDH-based drug delivery systems, LDHs for cancer diagnosis and therapy, tissue engineering, coatings, functional membranes, and biosensors, are comprehensively discussed. From these various biomedical research fields, it can be seen that there is great potential and possibility for the use of LDHs in biomedical applications. However, at the same time, it must be recognized that the actual clinical translation of LDHs is still very limited. Therefore, the current limitations of related research on LDHs are discussed by combining limited examples of actual clinical translation with requirements for clinical translation of biomaterials. Finally, an outlook on future research related to LDHs is provided.

Indexed as

Biocompatible MaterialsDrug Delivery SystemsHydroxidesTissue EngineeringAnimalsBiosensing TechniquesHumansBiocompatible MaterialsHydroxidesbiomedical applicationdrug deliveryexchangeabilitylayered double hydroxidesnanotheranostics

Identifiers

PMID38501901
PMCPMC11132086

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.