Evidence map›Paper›PMID 38509177›Full record

ArticleScientific reports2024

Associations between dietary inflammatory index and stroke risk: based on NHANES 2005-2018.

Ruixian Huang, Fengxia Lai, Le Zhao, Jingjing Zhang, Hao Chen, Shuang Wang, Canjin Chen, Wenhao Wang, Zhenhua Mai, Yuanlin Ding and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  10. Prolonged exposure to leisure screen time notably accelerates biological aging: Evidence from observational studies and genetic associations.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ruixian Huang *Department of Epidemiology and Medical Statistics, School of Public Health, Guangdong Medical University, Dongguan, 523808, China.
Fengxia Lai *Department of Epidemiology and Medical Statistics, School of Public Health, Guangdong Medical University, Dongguan, 523808, China.
Le ZhaoDepartment of Epidemiology and Medical Statistics, School of Public Health, Guangdong Medical University, Dongguan, 523808, China.
Jingjing ZhangDepartment of Epidemiology and Medical Statistics, School of Public Health, Guangdong Medical University, Dongguan, 523808, China.
Hao ChenDepartment of Epidemiology and Medical Statistics, School of Public Health, Guangdong Medical University, Dongguan, 523808, China.
Shuang WangDepartment of Epidemiology and Medical Statistics, School of Public Health, Guangdong Medical University, Dongguan, 523808, China.
Canjin ChenDepartment of Epidemiology and Medical Statistics, School of Public Health, Guangdong Medical University, Dongguan, 523808, China.
Wenhao WangDepartment of Epidemiology and Medical Statistics, School of Public Health, Guangdong Medical University, Dongguan, 523808, China.
Zhenhua MaiDepartment of Epidemiology and Medical Statistics, School of Public Health, Guangdong Medical University, Dongguan, 523808, China. zhenhuamai@gdmu.edu.cn.
Yuanlin DingDepartment of Epidemiology and Medical Statistics, School of Public Health, Guangdong Medical University, Dongguan, 523808, China. gdmudyl@163.com.
Danli KongDepartment of Epidemiology and Medical Statistics, School of Public Health, Guangdong Medical University, Dongguan, 523808, China. gdmckdl@163.com.

Funding

Discipline Construction Project of Guangdong Medical University 4SG21276PGuangdong Basic and Applied Basic Research Fund Project 2022A1515220196Guangdong Medical University's 2021 school-level undergraduate teaching quality and teaching reform project 1JG21086The Basic and Applied Basic Research Foundation of Guangdong Province Regional Joint Fund Project (The Key Project) 2020B1515120021
6 · The paper itself

Abstract

The dietary inflammatory index (DII) is a measure of the inflammatory potential of the diet and is closely associated with insulin resistance (IR) and stroke. And IR may play an important role in the development of stroke. Therefore, this study aimed to evaluate the relationship between DII and stroke risk while delving into the potential role of IR in this association. We analyzed data from the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2018, performing weighted univariate analyses, logistic regression, and mediation analyses. At baseline, 3.89% of participants developed stroke, and we observed stroke patients exhibited higher DII scores. After adjusting for covariates, compared to participants in the first quartile of DII scores, those in the third quartile and fourth quartile had increased odds of experiencing a stroke (OR: 1.78, 95% CI: 1.18-2.68) and (OR: 1.70, 95% CI: 1.16-2.50), respectively. Moreover, a significant dose-response relationship was observed (P-trend < 0.05). However, there was no observed interaction between DII and homeostatic model assessment-IR (HOMA-IR) concerning stroke risk, and HOMA-IR did not mediate the association between DII and stroke. In summary, our study elucidated the significant association between DII and stroke risk, independent of IR. This insight suggests that an anti-inflammatory diet may serve as an effective strategy for stroke prevention.

Indexed as

Insulin ResistanceStrokeDietHumansInflammationNutrition SurveysDietary inflammatory indexInsulin resistanceMediation analysisNational Health and Nutrition Examination SurveyStroke

Identifiers

PMID38509177
PMCPMC10954724

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.