Evidence map›Paper›PMID 38509933›Full record

ArticleHeliyon2024

Impact of anesthetics on rat hippocampus and neocortex: A comprehensive proteomic study based on label-free mass spectrometry.

David Astapenko, Marie Vajrychova, Ivo Fabrik, Rudolf Kupcik, Kristyna Pimkova, Vojtech Tambor, Vera Radochova, Vladimir Cerny

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

David AstapenkoDepartment of Anesthesiology and Intensive Care, University Hospital Hradec Kralove, Charles University, Faculty of Medicine in Hradec Kralove, Hradec Kralove, Czech Republic.
Marie VajrychovaBiomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
Ivo FabrikBiomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
Rudolf KupcikBiomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
Kristyna PimkovaBiomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
Vojtech TamborBiomedical Research Center, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
Vera RadochovaVivarium Department, Faculty of Military Health Sciences, University of Defence, Brno, Czech Republic.
Vladimir CernyDepartment of Anesthesiology and Intensive Care, University Hospital Hradec Kralove, Charles University, Faculty of Medicine in Hradec Kralove, Hradec Kralove, Czech Republic.
University Hospital Hradec Králové · CZCharles University · CZTechnical University of Liberec · CZUniversity of Defence · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anesthesia is regarded as an important milestone in medicine. However, the negative effect on memory and learning has been observed. In addition, the impact of anesthetics on postoperative cognitive functions is still discussed. In this work,

Indexed as

AnestheticsApoptosisGABA signalingHippocampusLabel-free proteomicsLong-term potentiationNeocortexNMDARVDAC

Identifiers

PMID38509933
PMCPMC10950665
OpenAlexW4392474029

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.