Evidence map›Paper›PMID 38510643›Full record

ArticleAutophagy reports2023

MALT-1 shortens lifespan by inhibiting autophagy in the intestine of

Julie Vérièpe-Salerno, Silvia Podavini, Marcus J C Long, Irina Kolotuev, Muriel Cuendet, Margot Thome

Open access · diamondAbstract read
In one paragraph

Article in Autophagy reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Autophagy: A Double-Edged Sword in the Aging ofInternational journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Julie Vérièpe-SalernoDepartment of Immunobiology, Faculty of Biology and Medicine, University of Lausanne, Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland.
Silvia PodaviniDepartment of Immunobiology, Faculty of Biology and Medicine, University of Lausanne, Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland.
Marcus J C LongDepartment of Immunobiology, Faculty of Biology and Medicine, University of Lausanne, Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland.
Irina KolotuevElectron Microscopy Facility, University of Lausanne, Quartier Sorge - Biophore, CH-1015 Lausanne, Switzerland.
Muriel CuendetSchool of Pharmaceutical Sciences, University of Geneva, Rue Michel-Servet 1, CH-1211 Geneva, Switzerland.
Margot ThomeDepartment of Immunobiology, Faculty of Biology and Medicine, University of Lausanne, Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland.ORCID 0000-0002-5656-2139
University of Lausanne · CHUniversity of Geneva · CH

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440Swiss National Science Foundation 184749
6 · The paper itself

Abstract

The caspase-like protease MALT1 promotes immune responses and oncogenesis in mammals by activating the transcription factor NF-κB. MALT1 is remarkably conserved from mammals to simple metazoans devoid of NF-κB homologs, like the nematode

Indexed as

AgingATG-13autolysosomeautophagosomeBeclin-1chloroquineelectron microscopyLGG-2lifespanstarvation

Identifiers

PMID38510643
PMCPMC7615756
OpenAlexW4388528433

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.