Evidence map›Paper›PMID 38512807›Full record

ArticleAmerican journal of respiratory cell and molecular biology2024

Kisspeptin/KISS1R Signaling Modulates Human Airway Smooth Muscle Cell Migration.

Premanand Balraj, Nilesh Sudhakar Ambhore, Yogaraj S Ramakrishnan, Niyati A Borkar, Priyanka Banerjee, Mohammad Irshad Reza, Subashini Varadharajan, Ashish Kumar, Christina M Pabelick, Y S Prakash and 1 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 8 citations in OpenAlex.

  1. AhR activation inhibits DRP1-induced mitochondrial fission in airway smooth muscle during asthma.American journal of respiratory cell and molecular biology · 2026
    Article
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  11. Article
  12. Dissecting a Brake for Airway Smooth Muscle Cell Movement.American journal of respiratory cell and molecular biology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Premanand BalrajDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota.ORCID 0000-0002-1896-0419
Nilesh Sudhakar AmbhoreDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota.ORCID 0000-0002-9293-6062
Yogaraj S RamakrishnanDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota.ORCID 0009-0008-2831-6767
Niyati A BorkarDepartment of Anesthesiology and Perioperative Medicine, and.ORCID 0000-0002-7919-8798
Priyanka BanerjeeDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota.ORCID 0000-0001-5054-3095
Mohammad Irshad RezaDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota.ORCID 0000-0002-0013-2340
Subashini VaradharajanDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota.ORCID 0009-0007-2897-9651
Ashish KumarDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota.ORCID 0009-0009-3449-9165
Christina M PabelickDepartment of Anesthesiology and Perioperative Medicine, and.ORCID 0000-0002-4632-2174
Y S PrakashDepartment of Anesthesiology and Perioperative Medicine, and.ORCID 0000-0002-2968-224X
Venkatachalem SathishDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota.ORCID 0000-0001-9770-8299
North Dakota State University · USMayo Clinic · US

Funding

Tracking and Evaluation CoreU54GM128729 · NIGMS · UNIVERSITY OF NORTH DAKOTA · PI BASSON, MARC D. · 2018 to 2022
$20.3M
Neurotrophins in the LungR01HL088029 · NHLBI · MAYO CLINIC ROCHESTER · PI PRAKASH, Y. S. · 2009 to 2022
$5.9M
Kisspeptins in the AirwayR01HL146705 · NHLBI · NORTH DAKOTA STATE UNIVERSITY · PI VENKATACHALEM, SATHISH · 2020 to 2024
$2.2M
Nicotine, Airway Smooth Muscle and AsthmaR01HL142061 · NHLBI · MAYO CLINIC ROCHESTER · PI PABELICK, CHRISTINA MARIA, PRAKASH, Y. S. · 2019 to 2022
$2.0M
NHLBI NIH HHS R01 HL088029NHLBI NIH HHS R01-HL088029NHLBI NIH HHS R01 HL142061NHLBI NIH HHS R01-HL142061NHLBI NIH HHS R01 HL146705NHLBI NIH HHS R01-HL146705NIGMS NIH HHS U54 GM128729
6 · The paper itself

Abstract

Airway remodeling is a cardinal feature of asthma, associated with increased airway smooth muscle (ASM) cell mass and upregulation of extracellular matrix deposition. Exaggerated ASM cell migration contributes to excessive ASM mass. Previously, we demonstrated the alleviating role of Kp (kisspeptin) receptor (KISS1R) activation by Kp-10 in mitogen (PDGF [platelet-derived growth factor])-induced human ASM cell proliferation

Indexed as

Cell MovementKisspeptinsMyocytes, Smooth MuscleReceptors, Kisspeptin-1Signal TransductionActin Depolymerizing FactorsActinsAirway Remodelingcdc42 GTP-Binding ProteinCell ProliferationCells, CulturedCyclic AMPCyclic AMP-Dependent Protein KinasesHumansPlatelet-Derived Growth FactorReceptors, G-Protein-CoupledActin Depolymerizing FactorsActinscdc42 GTP-Binding ProteinCDC42 protein, humanCyclic AMPCyclic AMP-Dependent Protein KinasesKISS1 protein, humanKISS1R protein, humanKisspeptinsPlatelet-Derived Growth FactorReceptors, G-Protein-CoupledReceptors, Kisspeptin-1rhoA GTP-Binding ProteinRHOA protein, humanactin dynamicsairway remodelingasthmacAMP-dependent protein kinase Amitogen

Identifiers

PMID38512807
PMCPMC11160419
OpenAlexW4393032323

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.