Evidence map›Paper›PMID 38514191›Full record

ArticleeNeuro2024

Forebrain EAAT3 Overexpression Increases Susceptibility to Amphetamine-Induced Repetitive Behaviors.

Jared M Kopelman, Muhammad O Chohan, Alex I Hsu, Eric A Yttri, Jeremy Veenstra-VanderWeele, Susanne E Ahmari

Open access · goldAbstract read
In one paragraph

Article in eNeuro, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jared M KopelmanDepartment of Psychiatry, Translational Neuroscience Program, University of Pittsburgh, Pittsburgh, Pennsylvania 15260.
Muhammad O ChohanDepartment of Psychiatry, Columbia University, New York, New York 10032.ORCID https://orcid.org/0000-0002-9359-3700
Alex I HsuDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania 15260.
Eric A YttriDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania 15260.
Jeremy Veenstra-VanderWeeleDepartment of Psychiatry, Columbia University, New York, New York 10032 jeremy.veenstra@nyspi.columbia.edu ahmarise@upmc.edu.
Susanne E AhmariDepartment of Psychiatry, Translational Neuroscience Program, University of Pittsburgh, Pittsburgh, Pennsylvania 15260 jeremy.veenstra@nyspi.columbia.edu ahmarise@upmc.edu.ORCID https://orcid.org/0000-0003-4576-076X
Carnegie Mellon University · USNew York Psychoanalytic Society and Institute · USUniversity of Pittsburgh · US

Funding

Investigation of EAAT3 in OCD PathophysiologyR01MH114296 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI AHMARI, SUSANNE ELIZABETH, VEENSTRA-VANDERWEELE, JEREMY · 2017 to 2021
$2.7M
Examining the Role of EAAT3 in OCD-like BehaviorF30MH115517 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KOPELMAN, JARED MICHAEL · 2017 to 2019
$149k
NIMH NIH HHS F30 MH115517NIMH NIH HHS R01 MH114296
6 · The paper itself

Abstract

Obsessive-compulsive disorder (OCD) is a debilitating psychiatric disorder characterized by intrusive obsessive thoughts and compulsive behaviors. Multiple studies have shown the association of polymorphisms in the

Indexed as

AmphetamineExcitatory Amino Acid Transporter 3Obsessive-Compulsive DisorderAnimalsCorpus StriatumDisease Models, AnimalMiceAmphetamineExcitatory Amino Acid Transporter 3Slc1a1 protein, mouseamphetaminebasal gangliaD1-MSNDeepLabCutimmediate early geneneurotransmitter transporterspreclinical modelrepetitive behaviorRNAScopestriatum

Identifiers

PMID38514191
PMCPMC11012153
OpenAlexW4393028798

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.