ArticleNature communications2024
Switching action modes of miR408-5p mediates auxin signaling in rice.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 33 citations in OpenAlex.
- The transcription factorHorticulture research · 2026Article
- High-throughput sequencing and analysis of target genes uncover microRNA-mediated responses to low-temperature stress in Medicago falcata.BMC genomics · 2026Article
- RNA regulation in plants.Science China. Life sciences · 2026Review
- miR408-5p and miR408-3p cooperatively reduce cadmium uptake and accumulation in rice.PLoS biology · 2026Article
- LncRNA7503 decreases peach (Prunus persica) branch number and angle by inducing pre-miR395a degradation and reducing bioactive BR content.Molecular horticulture · 2026Article
- Article
- Comprehensive genomic and haplotype analysis of the phytocyanin gene family reveals evolutionary expansion and functional diversification in Setaria italica.Plant cell reports · 2026Article
- Translational control in plants: from basic mechanisms to environmental and developmental responses.The Plant journal : for cell and molecular biology · 2026Review
- Plant microRNA maturation and function.Nature reviews. Molecular cell biology · 2026Review
- MicroRNA164d suppresses the HvNAC92-HvHKT1;5 module to enhance salinity tolerance in barley.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Post-transcriptional and post-translational regulation of anthocyanin biosynthesis in sweetpotato by Ib-miR2111 and IbKFB: Implications for health promotion.Journal of advanced research · 2025Article
- Rice-specific miR1850.1 targets NPR3 to regulate cold stress response.Plant communications · 2025Article
- Function of floral fragrance-related microRNAs and their targets in Hedychium coronarium.BMC genomics · 2025Article
- A virulent milRNA ofHorticulture research · 2025Article
- MicroRNA gatekeepers: Orchestrating rhizospheric dynamics.Journal of integrative plant biology · 2025Review
- Genome-wide identification, transcriptional profiling, and miRNA-binding site analysis of theFrontiers in plant science · 2025Article
- Advances in auxin synthesis, transport, and signaling in rice: implications for stress resilience and crop improvement.Frontiers in plant science · 2024Review
Corrections and comments
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Authors and funding
14 authors at 5 institutions in 1 country.
Funding
Abstract
MicroRNAs (miRNAs) play fundamental roles in many developmental and physiological processes in eukaryotes. MiRNAs in plants generally regulate their targets via either mRNA cleavage or translation repression; however, which approach plays a major role and whether these two function modes can shift remains elusive. Here, we identify a miRNA, miR408-5p that regulates AUXIN/INDOLE ACETIC ACID 30 (IAA30), a critical repressor in the auxin pathway via switching action modes in rice. We find that miR408-5p usually inhibits IAA30 protein translation, but in a high auxin environment, it promotes the decay of IAA30 mRNA when it is overproduced. We further demonstrate that IDEAL PLANT ARCHITECTURE1 (IPA1), an SPL transcription factor regulated by miR156, mediates leaf inclination through association with miR408-5p precursor promoter. We finally show that the miR156-IPA1-miR408-5p-IAA30 module could be controlled by miR393, which silences auxin receptors. Together, our results define an alternative auxin transduction signaling pathway in rice that involves the switching of function modes by miR408-5p, which contributes to a better understanding of the action machinery as well as the cooperative network of miRNAs in plants.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.