Evidence map›Paper›PMID 38514744›Full record

ArticleScientific reports2024

The effect of cognitive reappraisal and early-life maternal care on neuroendocrine stress responses.

Ulrike U Bentele, Elea S C Klink, Annika B E Benz, Maria Meier, Raphaela J Gaertner, Bernadette F Denk, Stephanie J Dimitroff, Eva Unternaehrer, Jens C Pruessner

Abstract read
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In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ulrike U BenteleDepartment of Psychology, Division of Neuropsychology, University of Konstanz, Universitaetsstrasse 10, 78464, Constance, Germany. ulrike.bentele@uni.kn.ORCID 0000-0002-3121-1957
Elea S C KlinkDepartment of Psychology, Division of Neuropsychology, University of Konstanz, Universitaetsstrasse 10, 78464, Constance, Germany.
Annika B E BenzDepartment of Psychology, Division of Neuropsychology, University of Konstanz, Universitaetsstrasse 10, 78464, Constance, Germany.
Maria MeierDepartment of Psychology, Division of Neuropsychology, University of Konstanz, Universitaetsstrasse 10, 78464, Constance, Germany.ORCID 0000-0002-1655-5479
Raphaela J GaertnerDepartment of Psychology, Division of Neuropsychology, University of Konstanz, Universitaetsstrasse 10, 78464, Constance, Germany.
Bernadette F DenkDepartment of Psychology, Division of Neuropsychology, University of Konstanz, Universitaetsstrasse 10, 78464, Constance, Germany.
Stephanie J DimitroffDepartment of Psychology, University of Montana, Montana, 59812, USA.
Eva UnternaehrerDepartment of Psychology, Division of Neuropsychology, University of Konstanz, Universitaetsstrasse 10, 78464, Constance, Germany.ORCID 0000-0002-3507-1883
Jens C PruessnerDepartment of Psychology, Division of Neuropsychology, University of Konstanz, Universitaetsstrasse 10, 78464, Constance, Germany.ORCID 0000-0002-8582-2980

Funding

Deutsche Forschungsgemeinschaft EXC 2117-422037984
6 · The paper itself

Abstract

Early-life adversity (ELA) is related to profound dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, reflected in both, blunted or exaggerated cortisol stress responses in adulthood. Emotion regulation strategies such as cognitive reappraisal might contribute to this inconsistent finding. Here, we investigate an interaction of early-life maternal care (MC), where low MC represents a form of ELA, and instructed emotion regulation on cortisol responses to acute stress. Ninety-three healthy young women were assigned to a low (n = 33) or high (n = 60) MC group, based on self-reported early-life MC. In the laboratory, participants received regulation instructions, asking to cognitively reappraise (reappraisal group, n = 45) or to focus on senses (control group, n = 48) during subsequent stress exposure, induced by the Trier Social Stress Test. Salivary cortisol and subjective stress levels were measured repeatedly throughout the experiment. Multilevel model analyses confirmed a MC by emotion regulation interaction effect on cortisol trajectories, while controlling for hormonal status. Individuals with low MC in the control compared with the reappraisal group showed increased cortisol responses; individuals with high MC did not differ. These results highlight the significance of emotion regulation for HPA axis stress regulation following ELA exposure. They provide methodological and health implications, indicating emotion regulation as a promising target of treatment interventions for individuals with a history of ELA.

Indexed as

Hypothalamo-Hypophyseal SystemStress, PsychologicalCognitionFemaleHumansHydrocortisonePituitary-Adrenal SystemSalivaHydrocortisone

Identifiers

PMID38514744
PMCPMC10957921

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.