SynthesisBMC musculoskeletal disorders2024
Effects of mind-body exercise on knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials.
Synthesis in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 8 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- Efficacy of different exercise interventions on cognitive function in adults with major depressive disorder and subthreshold depression: a systematic review with pairwise and network meta-analyses.European archives of psychiatry and clinical neuroscience · 2026Pooled it
- Comparative efficacy of traditional and modern mind-body exercises in middle-aged and older adults with knee osteoarthritis: a network meta-analysis of randomized controlled trials.Frontiers in medicine · 2026Pooled it
- The efficacy and safety of pilates exercise in patients with knee osteoarthritis: a systematic review with meta-analysis of randomized controlled trials.Annals of medicine · 2025Pooled it
- Comparative efficacy and safety of exercise modalities in knee osteoarthritis: systematic review and network meta-analysis.BMJ (Clinical research ed.) · 2025Pooled it
- Effectiveness of exercise therapy in patients with knee osteoarthritis: an overview of systematic reviews.BMJ open · 2025Pooled it
- Comparative efficacy of mind-body exercise for pain, function, quality of life in knee osteoarthritis: a systematic review and network meta-analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- Effect of active mind-body movement therapies on older osteoarthritis: a systematic review and meta-analysis of randomized controlled trials.Frontiers in public health · 2025Pooled it
- Effect of tele-rehabilitation guided intervention on pain and function in middle-aged and older adult patients with knee osteoarthritis: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Multi-domain Online Therapeutic Investigation Of Neurocognition (MOTION) - A randomized comparative-effectiveness study of two remotely delivered mind-body interventions for older adults with cognitive decline.Contemporary clinical trials · 2025Trial
- The effect of exercise on clinical pain: a systematic umbrella review and meta-meta-analysis.Pain reports · 2026Article
- Effects of land-based exercise on knee joint proprioception in individuals with knee osteoarthritis: A systematic review and meta-analysis.Sports medicine and health science · 2026Review
- Evidence map of Tai Chi interventions for older adults.Frontiers in public health · 2026Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effect of mind-body exercise on improving knee osteoarthritis (KOA) and thereby informing osteoarthritis exercise rehabilitation.
methodsThe China National Knowledge Infrastructure (CNKI), Wanfang, PubMed/Medline, Cochrane Library, Web of Science, EBSCO, Embase, Scopus, and ProQuest databases were searched to identify randomized controlled trials (RCTs) that involved tai chi, yoga, and baduanjin interventions for KOA. The search period ranged from inception to October 25, 2022. The methodological quality of the included studies was evaluated by the Cochrane risk of bias assessment tool, and the included data were statistically analyzed and plotted using Review Manager 5.3 and Stata 14.0 software.
resultsWe included 17 articles with a total of 1122 patients. Compared with the control group, mind-body exercise significantly improved patient pain (standardized mean difference (SMD) = -0.65, 95% confidence interval (CI) [-0.87, -0.42], p < 0.00001), stiffness (SMD = -0.75, 95% CI [-1.05, -0.45], p < 0.00001), physical function (SMD = -0.82, 95% CI [-1.03, -0.62], p < 0.00001), mental health (SMD = 0.31, 95% CI [0.11, 0.51], p = 0.002), and depression (SMD = -0.32, 95% CI [-0.50, -0.15], p = 0.0003). In terms of motor ability, mind-body exercise significantly increased the 6-min walking distance (SMD = 18.45, 95% CI [5.80, 31.10], p = 0.004) and decreased timed up and go test time (SMD = -1.15, 95% CI [-1.71, -0.59], p < 0.0001).
conclusionsThe current study showed that mind-body exercise is safe and effective for KOA patients. However, given the methodological limitations of the included studies, additional high-quality evidence is needed to support the conclusions of this study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.