Evidence map›Paper›PMID 38515547›Full record

ArticleNeurotrauma reports2024

Longitudinal Biochemical and Behavioral Alterations in a Gyrencephalic Model of Blast-Related Mild Traumatic Brain Injury.

Shiyu Tang, Su Xu, Donna Wilder, Alexandre E Medina, Xin Li, Gary M Fiskum, Li Jiang, Venkata R Kakulavarapu, Joseph B Long, Rao P Gullapalli and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurotrauma reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Shiyu TangDepartment of Diagnostic Radiology and Nuclear Medicine, Trauma, and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Su XuDepartment of Diagnostic Radiology and Nuclear Medicine, Trauma, and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Donna WilderBlast Induced Neurotrauma Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Alexandre E MedinaDepartment of Pediatrics, Trauma, and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Xin LiDepartment of Diagnostic Radiology and Nuclear Medicine, Trauma, and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Gary M FiskumDepartment of Anesthesiology, Trauma, and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Li JiangDepartment of Diagnostic Radiology and Nuclear Medicine, Trauma, and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Venkata R KakulavarapuBlast Induced Neurotrauma Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Joseph B LongBlast Induced Neurotrauma Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Rao P GullapalliDepartment of Diagnostic Radiology and Nuclear Medicine, Trauma, and Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Venkatasivasai Sujith SajjaBlast Induced Neurotrauma Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
University of Maryland, Baltimore · USWalter Reed Army Institute of Research · USAdvanced Imaging Research (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blast-related traumatic brain injury (bTBI) is a major cause of neurological disorders in the U.S. military that can adversely impact some civilian populations as well and can lead to lifelong deficits and diminished quality of life. Among these types of injuries, the long-term sequelae are poorly understood because of variability in intensity and number of the blast exposure, as well as the range of subsequent symptoms that can overlap with those resulting from other traumatic events (e.g., post-traumatic stress disorder). Despite the valuable insights that rodent models have provided, there is a growing interest in using injury models using species with neuroanatomical features that more closely resemble the human brain. With this purpose, we established a gyrencephalic model of blast injury in ferrets, which underwent blast exposure applying conditions that closely mimic those associated with primary blast injuries to warfighters. In this study, we evaluated brain biochemical, microstructural, and behavioral profiles after blast exposure using

Indexed as

biochemical and behavioral alterationsferretin vivo magnetic resonance spectroscopymild TBIprimary blast

Identifiers

PMID38515547
PMCPMC10956534
OpenAlexW4392868328

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.