Evidence map›Paper›PMID 38519626›Full record

ArticleNPJ digital medicine2024

Digital twins for health: a scoping review.

Evangelia Katsoulakis, Qi Wang, Huanmei Wu, Leili Shahriyari, Richard Fletcher, Jinwei Liu, Luke Achenie, Hongfang Liu, Pamela Jackson, Ying Xiao and 3 more

Open access · goldAbstract readScoping Review
In one paragraph

Article in NPJ digital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 298 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
298citing papers in PubMed, 2 pooled it
164.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

298 citing papers in PubMed, 2 syntheses or guidelines pooled it, 472 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. New approach methodologies (NAMs) for preclinical and translational evaluation of mRNA-lipid nanoparticle (LNP) therapeutics.Journal of controlled release : official journal of the Controlled Release Society · 2026
    Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. The physiology of survival: Space.Experimental physiology · 2026
    Article
  19. Review
  20. Review

238 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 12 institutions in 1 country.

Evangelia KatsoulakisVA Informatics and Computing Infrastructure, Salt Lake City, UT, 84148, USA.
Qi WangDepartment of Mathematics, University of South Carolina, Columbia, SC, 29208, USA.
Huanmei WuDepartment of Health Services Administration and Policy, Temple University, Philadelphia, PA, 19122, USA.
Leili ShahriyariDepartment of Mathematics and Statistics, University of Massachusetts Amherst, Amherst, MA, 01003, USA.ORCID http://orcid.org/0000-0001-6234-8449
Richard FletcherDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Jinwei LiuDepartment of Computer and Information Sciences, Florida A&M University, Tallahassee, FL, 32307, USA.ORCID http://orcid.org/0000-0003-2298-5974
Luke AchenieDepartment of Chemical Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA, 24060, USA.
Hongfang LiuMcWilliams School of Biomedical Informatics, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Pamela JacksonPrecision Neurotherapeutics Innovation Program & Department of Neurosurgery, Mayo Clinic, Phoenix, AZ, 85003, USA.
Ying XiaoDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Tanveer Syeda-MahmoodIBM Almaden Research Center, San Jose, CA, 95120, USA.
Richard TuliDepartment of Radiation Oncology, University of South Florida, Tampa, FL, 33606, USA.
Jun DengDepartment of Therapeutic Radiology, Yale University, New Haven, CT, 06510, USA. Jun.Deng@yale.edu.
University of South Florida · USFlorida Agricultural and Mechanical University · USIBM Research - Almaden · USMassachusetts General Hospital · USMayo Clinic in Florida · USTemple University · USThe University of Texas Health Science Center at Houston · USUniversity of Massachusetts Amherst · USUniversity of Pennsylvania · USUniversity of South Carolina · USVirginia Tech · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of digital twins (DTs) has proliferated across various fields and industries, with a recent surge in the healthcare sector. The concept of digital twin for health (DT4H) holds great promise to revolutionize the entire healthcare system, including management and delivery, disease treatment and prevention, and health well-being maintenance, ultimately improving human life. The rapid growth of big data and continuous advancement in data science (DS) and artificial intelligence (AI) have the potential to significantly expedite DT research and development by providing scientific expertise, essential data, and robust cybertechnology infrastructure. Although various DT initiatives have been underway in the industry, government, and military, DT4H is still in its early stages. This paper presents an overview of the current applications of DTs in healthcare, examines consortium research centers and their limitations, and surveys the current landscape of emerging research and development opportunities in healthcare. We envision the emergence of a collaborative global effort among stakeholders to enhance healthcare and improve the quality of life for millions of individuals worldwide through pioneering research and development in the realm of DT technology.

Identifiers

PMID38519626
PMCPMC10960047
OpenAlexW4393094536

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.