Evidence map›Paper›PMID 38524158›Full record

ArticleSleep and biological rhythms2024

Restless legs syndrome, periodic limb movements of sleep, and subclinical cardiovascular disease.

Kevin J Hochstrasser, Steven C Rogers, Arshed Quyyumi, Dayna Johnson, Victoria Pak, Amit J Shah, David B Rye, Lynn Marie Trotti

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sleep and biological rhythms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kevin J HochstrasserDepartment of Neurology, Emory Sleep Center, Emory University School of Medicine, 12 Executive Park Dr NE, Atlanta, GA 30329 USA.
Steven C RogersDivision of Cardiology, Department of Internal Medicine, Emory University School of Medicine, Atlanta, USA.
Arshed QuyyumiDivision of Cardiology, Department of Internal Medicine, Emory University School of Medicine, Atlanta, USA.
Dayna JohnsonDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, USA.
Victoria PakEmory Nell Hodgson Woodruff School of Nursing, Atlanta, USA.
Amit J ShahDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, USA.
David B RyeDepartment of Neurology, Emory Sleep Center, Emory University School of Medicine, 12 Executive Park Dr NE, Atlanta, GA 30329 USA.
Lynn Marie TrottiDepartment of Neurology, Emory Sleep Center, Emory University School of Medicine, 12 Executive Park Dr NE, Atlanta, GA 30329 USA.ORCID 0000-0003-2329-6847
Emory University · USEmory and Henry College · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Atlanta Clinical and Translational Science Institute (KL2)KL2RR025009 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$2.9M
Antibiotic-mediated improvements in vigilance: mechanisms of action of clarithromycin in hypersomnia syndromesR01NS111280 · NINDS · EMORY UNIVERSITY · PI TROTTI, LYNN MARIE · 2019 to 2023
$2.2M
NCATS NIH HHS UL1 TR002378NCRR NIH HHS KL2 RR025009NINDS NIH HHS R01 NS111280
6 · The paper itself

Abstract

Restless legs syndrome (RLS) and periodic limb movements of sleep (PLMS) have been variably implicated in risk for cardiovascular disease (CVD), but there is lack of consensus on these relationships. We sought to assess subclinical CVD measures and RLS/PLMS in a large cohort to further evaluate these associations. The Emory Center for Health Discovery and Well Being cohort is composed of employed adults, with subclinical CVD measures including endothelial function (flow-mediated vasodilation), microvascular function (reactive hyperemia index, RHI), arterial stiffness (pulse wave velocity and augmentation index), and carotid intima-media thickness (cIMT). Participants were grouped based on presence ( Supplementary Information: The online version contains supplementary material available at 10.1007/s41105-023-00497-7.

Indexed as

Cardiovascular diseaseCarotid arteryIntima-media thicknessPeriodic limb movements of sleepRestless legs syndrome

Identifiers

PMID38524158
PMCPMC10959898
OpenAlexW4388221281

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.