ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2024
Clinical activity in general practice before sarcoma diagnosis: an Australian cohort study.
Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- Patients' experiences of the path to sarcoma diagnosis: a qualitative systematic review and thematic synthesis.BMJ open · 2026Pooled it
- Observational
- Decision support tools for pancreatic cancer detection: external validation in Australian primary care - a retrospective cohort study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026Article
- Risk Factors, Clinical Manifestations, and Treatment Outcomes of Primary Bone Sarcomas.Saudi medical journal · 2026Article
- Use of healthcare services and prescription medication prior to sarcoma diagnosis in children, adolescents, and young adults in 1997-2020: a population-based cohort study.Cancer causes & control : CCC · 2025Article
- Diagnostic Delay in Soft Tissue Sarcomas: A Review.Cancers · 2025Review
- The Prediagnostic General Practitioners' Pathway of Gastrointestinal Stromal Tumor Patients: A Real-World Data Study.Cancers · 2025Article
- Challenges of diagnosing rare cancers in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2024Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncreased time to diagnosis in sarcoma is associated with poor prognosis and patient outcomes. Research is needed to identify whether opportunities to expedite the diagnosis of sarcoma in general practice exist.
aimTo examine pre-diagnostic GP clinical activity before sarcoma diagnosis. DESIGN AND
settingAn Australian retrospective cohort study using hospital registry data (Australian Comprehensive Cancer Outcomes and Research Database [ACCORD]) linked to two primary care datasets (Patron and MedicineInsight).
methodThe frequency of general practice healthcare utilisation events (general practice attendances, prescriptions, blood test, and imaging requests) were compared in 377 patients with soft tissue sarcoma (STS) and 64 patients with bone sarcoma (BS) in the year pre-diagnosis. Poisson regression models were used to calculate monthly incidence rate ratios (IRR) for the 24 months pre-diagnosis and estimate inflection points for when healthcare use started to increase from baseline.
resultsIn the 6 months pre-diagnosis, patients with sarcoma had a median of 3-4 general practice attendances, around one-third had a GP imaging request (33% [
conclusionPatients with sarcoma have increased GP clinical activity from 6 months pre-diagnosis, indicating a diagnostic window where potential opportunities exist for earlier diagnosis. Interventions to help identify patients and promote appropriate use of imaging and direct specialist centre referrals could improve earlier diagnosis and patient outcomes.
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