Evidence map›Paper›PMID 38529602›Full record

ReviewCurrent medicinal chemistry2024

Fragment-based Drug Discovery Strategy and its Application to the Design of SARS-CoV-2 Main Protease Inhibitor.

Yu Jiang, Yingnan Wu, Jing Wang, Yuheng Ma, Hui Yu, Zhanli Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yu JiangInner Mongolia Key Laboratory of Disease-Related Biomarkers, The Second Affiliated Hospital, Baotou Medical College, Baotou, China.
Yingnan WuCollege of Pharmacy, Inner Mongolia Medical University, Hohhot, China.
Jing WangCollege of Pharmacy, Inner Mongolia Medical University, Hohhot, China.
Yuheng MaCollege of Pharmacy, Inner Mongolia Medical University, Hohhot, China.
Hui YuSchool of Basic Medicine, Baotou Medical College, Baotou, China.
Zhanli WangInner Mongolia Key Laboratory of Disease-Related Biomarkers, The Second Affiliated Hospital, Baotou Medical College, Baotou, China.
Baotou Medical College · CNInner Mongolia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe Acute Respiratory Syndrome Coronavirus Type 2 (SARS-CoV-2) emerged at the end of 2019, causing a highly infectious and pathogenic disease known as 2019 coronavirus disease. This disease poses a serious threat to human health and public safety. The SARS-CoV-2 main protease (M

Indexed as

Antiviral AgentsCoronavirus 3C ProteasesDrug DesignDrug DiscoverySARS-CoV-2COVID-19COVID-19 Drug TreatmentHumansPandemicsProtease InhibitorsAntiviral AgentsCoronavirus 3C ProteasesProtease Inhibitorscovaxifragment-based drug discoveryinhibitormain proteaseritonavir.SARS-CoV-2

Identifiers

PMID38529602
OpenAlexW4393182692

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.