ArticleThe clinical respiratory journal2024
Pleural fluid characteristics of patients with COVID-19 infection.
Article in The clinical respiratory journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
- Case report: A rare case of gelatinous pericardial effusion in a COVID-19 positive breast cancer patient.Frontiers in oncology · 2026Article
- Analyzing pleural fluid attributes in SARS-CoV-2 infection: a systematic review.Journal of thoracic disease · 2025Review
- Hepatic dysfunction in individuals with COVID-19 and its impact on pregnancy outcomes.Medicine · 2025Article
- Rates of PCR Positivity of Pleural Drainage Fluid in COVID-19 Patients: Is It Expected?Life (Basel, Switzerland) · 2024Article
- Pleural fluid characteristics of patients with COVID-19 infection.The clinical respiratory journal · 2024Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPleural effusions are known to occur in many cases of COVID-19. Data on typical characteristics of COVID-19-associated pleural effusions are limited. The goal of this project was to characterize the pleural fluid from patients with COVID-19.
methodsWe retrospectively collected electronic medical record data from adults hospitalized at a large metropolitan hospital system with COVID-19 infection who had a pleural effusion and a thoracentesis performed. We assessed pleural fluid characteristics and applied Light's criteria.
resultsWe identified 128 effusions from 106 unique patients; 45.4% of the effusions had fluid/serum protein ratio greater than 0.5, 33.9% had fluid/serum lactate dehydrogenase (LDH) greater than 0.6, and 56.2% had fluid LDH greater than 2/3 of the serum upper limit of normal. Altogether, 68.5% of effusions met at least one of these three characteristics and therefore were exudative by Light's criteria. The white blood cell (WBC) differential was predominantly lymphocytic (mean 42.8%) or neutrophilic (mean 28.7%); monocytes (mean 12.7%) and eosinophils (mean 2.5%) were less common.
conclusionWe demonstrate that 68.5% of pleural effusions in patients with COVID-19 infection were exudative and hypothesize that COVID-19-associated pleural effusions are likely to be exudative with WBC differential more likely to be predominantly lymphocytic.
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Registered trials
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