ArticleNature communications2024
Genetic similarity between relatives provides evidence on the presence and history of assortative mating.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 25 citations in OpenAlex.
- Multivariate maternal effects across the internalizing-externalizing spectrum in childhood: results from the Norwegian mother, father, and child cohort study.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Subclinical neuropsychiatric trait variation in parents of children with autism spectrum disorder: a cohort study.Molecular autism · 2026Article
- What does psychopathology research have to gain by studying all mental disorders at the same time?Journal of psychopathology and clinical science · 2026Article
- Familial healthy aging and longevity: the role of spouses.BMC medicine · 2026Article
- PGVDA: a pathway-aggregated genetic dosage framework for interpretable disease classification using machine learning.Briefings in bioinformatics · 2026Article
- Personality Genomics.Annual review of psychology · 2026Review
- Statistical methods to disentangle genetic effects influencing infertility and early fetal viability with a genome-wide application.PLoS genetics · 2025Article
- Diet as a source of the non-direct genetic effects in metabolic traits: evidence from a family-based GWAS study.Human genetics · 2025Article
- PIGEON: a statistical framework for estimating gene-environment interaction for polygenic traits.Nature human behaviour · 2025Article
- Beyond additive genetic effects: Explaining family resemblance in school performance across millions of pairs of Norwegian relatives.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Understanding indirect assortative mating and its intergenerational consequences for educational attainment.Nature communications · 2025Article
- The genetic and environmental composition of socioeconomic status in Norway.Nature communications · 2025Article
- Socio-economic status is a social construct with heritable components and genetic consequences.Nature human behaviour · 2025Review
- Differentiating mechanism from outcome for ancestry-assortative mating in admixed human populations.Genetics · 2025Article
- Familial confounding in the associations between maternal health and autism.Nature medicine · 2025Article
- Differentiating mechanism from outcome for ancestry-assortative mating in admixed human populations.bioRxiv : the preprint server for biology · 2024Article
- Non-random mating patterns within and across education and mental and somatic health.Nature communications · 2024Article
- Screening embryos for polygenic disease risk: a review of epidemiological, clinical, and ethical considerations.Human reproduction update · 2024Review
- Genomic predictions under different genetic architectures are impacted by mating designs.Veterinary and animal science · 2024Article
- Non-random Mating Patterns in Education, Mental, and Somatic Health: A Population Study on Within- and Cross-Trait Associations.medRxiv : the preprint server for health sciences · 2024Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Assortative mating - the non-random mating of individuals with similar traits - is known to increase trait-specific genetic variance and genetic similarity between relatives. However, empirical evidence is limited for many traits, and the implications hinge on whether assortative mating has started recently or many generations ago. Here we show theoretically and empirically that genetic similarity between relatives can provide evidence on the presence and history of assortative mating. First, we employed path analysis to understand how assortative mating affects genetic similarity between family members across generations, finding that similarity between distant relatives is more affected than close relatives. Next, we correlated polygenic indices of 47,135 co-parents from the Norwegian Mother, Father, and Child Cohort Study (MoBa) and found genetic evidence of assortative mating in nine out of sixteen examined traits. The same traits showed elevated similarity between relatives, especially distant relatives. Six of the nine traits, including educational attainment, showed greater genetic variance among offspring, which is inconsistent with stable assortative mating over many generations. These results suggest an ongoing increase in familial similarity for these traits. The implications of this research extend to genetic methodology and the understanding of social and economic disparities.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.