Evidence map›Paper›PMID 38533486›Full record

ArticleDevelopmental psychobiology2024

Maternal oxytocin treatment at birth increases epigenetic age in male offspring.

Joshua S Danoff, C Sue Carter, Juozas Gordevičius, Milda Milčiūtė, Robert T Brooke, Jessica J Connelly, Allison M Perkeybile

Open access · hybridAbstract read
In one paragraph

Article in Developmental psychobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Joshua S DanoffDepartment of Psychology, University of Virginia, Charlottesville, VA.
C Sue CarterDepartment of Psychology, University of Virginia, Charlottesville, VA.
Juozas GordevičiusEpigenetic Clock Development Foundation, Torrance, CA.
Milda MilčiūtėEpigenetic Clock Development Foundation, Torrance, CA.
Robert T BrookeEpigenetic Clock Development Foundation, Torrance, CA.
Jessica J ConnellyDepartment of Psychology, University of Virginia, Charlottesville, VA.
Allison M PerkeybileDepartment of Psychology, University of Virginia, Charlottesville, VA.
Epigenetix (United States) · USIndiana University Bloomington · USRutgers, The State University of New Jersey · USUniversity of Virginia · US

Funding

Mechanisms of maternal brain changes with birth interventionsR01HD098117 · NICHD · UNIVERSITY OF VIRGINIA · PI JESSICA J CONNELLY, Allison M. Perkeybile · 2019 to 2026
$4.9M
ImagingP01HD075750 · NICHD · TRUSTEES OF INDIANA UNIVERSITY · PI FERRIS, CRAIG F · 2014 to 2018
$4.3M
Epigenetic regulation of oxytocin pathways in the maternal brainF32HD092051 · NICHD · TRUSTEES OF INDIANA UNIVERSITY · PI PERKEYBILE, ALLISON M. · 2018 to 2020
$197k
NICHD NIH HHS F32 HD092051NICHD NIH HHS P01 HD075750NICHD NIH HHS R01 HD098117
6 · The paper itself

Abstract

Exogenous oxytocin (OT) is widely used to induce or augment labor with little understanding of the impact on offspring development. In rodent models, including the prairie vole (

Indexed as

OxytocinReceptors, OxytocinAnimalsArvicolinaeEpigenesis, GeneticFemaleHumansMaleMothersNucleus AccumbensPregnancySocial BehaviorOxytocinReceptors, Oxytocin

Identifiers

PMID38533486
PMCPMC10963051
OpenAlexW4390611077

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.