Evidence map›Paper›PMID 38533592›Full record

ArticleJournal of microbiology and biotechnology2024

Optimization of Culture Medium for the Production of an Exopolysaccharide (p-CY02) with Cryoprotective Activity by

Pilsung Kang, Sung Jin Kim, Ha Ju Park, Il Chan Kim, Se Jong Han, Joung Han Yim

Open access · greenAbstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Development of a CRISPR/Cas9-induced gene editing system forApplied and environmental microbiology · 2025
    Article
  2. Bioprospecting Antarctic Microorganisms: InvestigatingJournal of microbiology and biotechnology · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Pilsung KangDevelopment of Biomaterials from Polar Region, Korea Polar Research Institute, Incheon 21990, Republic of Korea.
Sung Jin KimDevelopment of Biomaterials from Polar Region, Korea Polar Research Institute, Incheon 21990, Republic of Korea.
Ha Ju ParkCRYOTECH Inc., Busan 46744, Republic of Korea.
Il Chan KimDevelopment of Biomaterials from Polar Region, Korea Polar Research Institute, Incheon 21990, Republic of Korea.
Se Jong HanDevelopment of Biomaterials from Polar Region, Korea Polar Research Institute, Incheon 21990, Republic of Korea.
Joung Han YimDevelopment of Biomaterials from Polar Region, Korea Polar Research Institute, Incheon 21990, Republic of Korea.
Korea Polar Research Institute · KRTongmyong University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When cells are exposed to freezing temperatures, high concentrations of cryoprotective agents (CPA) prevent ice crystal formation, thus enhancing cell survival. However, high concentrations of CPAs can also cause cell toxicity. Exopolysaccharides (EPSs) from polar marine environments exhibit lower toxicity and display effects similar to traditional CPA. In this study, we sought to address these issues by i) selecting strains that produce EPS with novel cryoprotective activity, and ii) optimizing culture conditions for EPS production. Sixty-six bacteria producing mucous substances were isolated from the Ross Sea (Antarctic Ocean) using solid marine agar plates. Among them,

Indexed as

Cell SurvivalCryoprotective AgentsCulture MediaPolysaccharides, BacterialPseudoalteromonasAntarctic RegionsCell LineDimethyl SulfoxideHaCaT CellsHumansSeawaterCryoprotective AgentsCulture MediaDimethyl SulfoxidePolysaccharides, BacterialCryoprotective activityexopolysaccharideresponse surface methodologythe Antarctic Sea

Identifiers

PMID38533592
PMCPMC11180913
OpenAlexW4393227032

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.