Evidence map›Paper›PMID 38533973›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2024

50-nm Gas-Filled Protein Nanostructures to Enable the Access of Lymphatic Cells by Ultrasound Technologies.

Qionghua Shen, Zongru Li, Yixian Wang, Matthew D Meyer, Marc T De Guzman, Janie C Lim, Han Xiao, Richard R Bouchard, George J Lu

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Protein engineering: status report.Protein engineering, design & selection : PEDS · 2026
    Review
  2. Review
  3. αvβ3-targeted gas vesicles for ultrasound molecular imaging of tumors.Frontiers in bioengineering and biotechnology · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Qionghua ShenDepartment of Bioengineering, Rice University, Houston, TX, 77030, USA.ORCID 0000-0002-2808-4408
Zongru LiDepartment of Bioengineering, Rice University, Houston, TX, 77030, USA.ORCID 0000-0003-1918-9707
Yixian WangDepartment of Chemistry, Rice University, Houston, TX, 77005, USA.ORCID 0009-0004-3093-6835
Matthew D MeyerShared Equipment Authority, Rice University, Houston, TX, 77005, USA.ORCID 0000-0002-0680-6123
Marc T De GuzmanDepartment of Bioengineering, Rice University, Houston, TX, 77030, USA.ORCID 0009-0006-6681-1297
Janie C LimDepartment of Bioengineering, Rice University, Houston, TX, 77030, USA.ORCID 0009-0007-2523-6000
Han XiaoDepartment of Bioengineering, Rice University, Houston, TX, 77030, USA.ORCID 0000-0002-4311-971X
Richard R BouchardDepartment of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.ORCID 0000-0003-4763-9875
George J LuDepartment of Bioengineering, Rice University, Houston, TX, 77030, USA.ORCID 0000-0002-4689-9686

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8M
Molecular Photoacoustic Imaging for Diagnostics and Therapy MonitoringR01EB028762 · NIBIB · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BOUCHARD, RICHARD R. · 2020 to 2024
$3.1M
Engineering Proteins with Noncanonical Amino AcidsR35GM133706 · NIGMS · RICE UNIVERSITY · PI Han Xiao · 2019 to 2026
$2.9M
Modulation of Epigenetic Target in the Bone to Treat Breast Cancer MetastasisR01CA277838 · NCI · RICE UNIVERSITY · PI Han Xiao, Xiang Zhang · 2023 to 2026
$2.6M
Sonomagnetic Imaging and Sonomechanical Control of Biological Processes in Deep TissuesR00EB024600 · NIBIB · RICE UNIVERSITY · PI LU, GEORGE J · 2020 to 2022
$744k
Ultrasensitive acoustic reporter proteins with engineered rupture-resistant shellsR21EB033607 · NIBIB · RICE UNIVERSITY · PI LU, GEORGE J · 2022 to 2024
$609k
Cancer Prevention and Research Institute of Texas RP190131Cancer Prevention and Research Institute of Texas RR170014Cancer Prevention and Research Institute of Texas RR190081G. Harold and Leila Y. Mathers Foundation MF-2012-01314Hearing Health FoundationJohn S. Dunn FoundationNCI NIH HHS P30 CA016672NCI NIH HHS P30CA016672NCI NIH HHS R00EB024600NCI NIH HHS R01 CA277838NCI NIH HHS R01CA277838NCI NIH HHS R21EB033607NIBIB NIH HHS R00 EB024600NIBIB NIH HHS R00EB024600NIBIB NIH HHS R01 EB028762NIBIB NIH HHS R21 EB033607NIBIB NIH HHS R21EB033607NIGMS NIH HHS R35 GM133706NIGMS NIH HHS R35GM133706Welch Foundation C-1970Welch Foundation C-2069
6 · The paper itself

Abstract

Ultrasound imaging and ultrasound-mediated gene and drug delivery are rapidly advancing diagnostic and therapeutic methods; however, their use is often limited by the need for microbubbles, which cannot transverse many biological barriers due to their large size. Here, the authors introduce 50-nm gas-filled protein nanostructures derived from genetically engineered gas vesicles(GVs) that are referred to as

Indexed as

NanostructuresAnimalsGasesLymph NodesMiceMicrobubblesProteinsUltrasonographyGasesgas vesicle proteinProteinsgas vesicleslymph nodesnanobubblesprotein nanostructuresultrasound

Identifiers

PMID38533973
PMCPMC11550859

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.