Evidence map›Paper›PMID 38534253›Full record

ReviewBiosensors2024

Aptamers and Nanobodies as New Bioprobes for SARS-CoV-2 Diagnostic and Therapeutic System Applications.

Ki Sung Park, Tae-In Park, Jae Eon Lee, Seo-Yeong Hwang, Anna Choi, Seung Pil Pack

Abstract readReview
In one paragraph

Review in Biosensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ki Sung ParkDepartment of Biotechnology and Bioinformatics, Korea University, Sejong 30019, Republic of Korea.
Tae-In ParkDepartment of Biotechnology and Bioinformatics, Korea University, Sejong 30019, Republic of Korea.ORCID 0000-0001-7000-9885
Jae Eon LeeDepartment of Biotechnology and Bioinformatics, Korea University, Sejong 30019, Republic of Korea.
Seo-Yeong HwangDepartment of Biotechnology and Bioinformatics, Korea University, Sejong 30019, Republic of Korea.
Anna ChoiDepartment of Biotechnology and Bioinformatics, Korea University, Sejong 30019, Republic of Korea.
Seung Pil PackDepartment of Biotechnology and Bioinformatics, Korea University, Sejong 30019, Republic of Korea.

Funding

National Research Foundation of Korea NRF-2021R1A2C2011564National Research Foundation of Korea NRF-2021R1A5A8032895National Research Foundation of Korea RS-2023-00244320
6 · The paper itself

Abstract

The global challenges posed by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic have underscored the critical importance of innovative and efficient control systems for addressing future pandemics. The most effective way to control the pandemic is to rapidly suppress the spread of the virus through early detection using a rapid, accurate, and easy-to-use diagnostic platform. In biosensors that use bioprobes, the binding affinity of molecular recognition elements (MREs) is the primary factor determining the dynamic range of the sensing platform. Furthermore, the sensitivity relies mainly on bioprobe quality with sufficient functionality. This comprehensive review investigates aptamers and nanobodies recently developed as advanced MREs for SARS-CoV-2 diagnostic and therapeutic applications. These bioprobes might be integrated into organic bioelectronic materials and devices, with promising enhanced sensitivity and specificity. This review offers valuable insights into advancing biosensing technologies for infectious disease diagnosis and treatment using aptamers and nanobodies as new bioprobes.

Indexed as

Aptamers, NucleotideBiosensing TechniquesCOVID-19Single-Domain AntibodiesCOVID-19 TestingHumansSARS-CoV-2Aptamers, NucleotideSingle-Domain Antibodiesaptamerbioprobebiosensing technologyinfectious disease diagnosisnanobodySARS-CoV-2

Identifiers

PMID38534253
PMCPMC10968798

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.