Evidence map›Paper›PMID 38534310›Full record

ArticleCells2024

Cannabidiol Exerts Anticonvulsant Effects Alone and in Combination with Δ

Yasaman Javadzadeh, Alexandra Santos, Mark S Aquilino, Shanthini Mylvaganam, Karolina Urban, Peter L Carlen

Open access · goldAbstract read
In one paragraph

Article in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yasaman JavadzadehKrembil Research Institute, University Health Network, Toronto, ON M5S 0T8, Canada.ORCID 0009-0005-6255-9672
Alexandra SantosKrembil Research Institute, University Health Network, Toronto, ON M5S 0T8, Canada.ORCID 0000-0002-7381-043X
Mark S AquilinoKrembil Research Institute, University Health Network, Toronto, ON M5S 0T8, Canada.
Shanthini MylvaganamKrembil Research Institute, University Health Network, Toronto, ON M5S 0T8, Canada.
Karolina UrbanAvicanna Inc., Toronto, ON M5G 1V2, Canada.
Peter L CarlenKrembil Research Institute, University Health Network, Toronto, ON M5S 0T8, Canada.ORCID 0000-0002-3339-8102
University Health Network · CA

Funding

Mitacs IT19836Ontario Centre of Innovation OCE-34038
6 · The paper itself

Abstract

Cannabinoids have shown potential in drug-resistant epilepsy treatment; however, we lack knowledge on which cannabinoid(s) to use, dosing, and their pharmacological targets. This study investigated (i) the anticonvulsant effect of Cannabidiol (CBD) alone and (ii) in combination with Delta-9 Tetrahydrocannabinol (Δ

Indexed as

CannabidiolCannabinoidsNeocortexAnimalsAnticonvulsantsDronabinolMiceReceptor, Serotonin, 5-HT1ASerotoninAnticonvulsantsCannabidiolCannabinoidsDronabinolReceptor, Serotonin, 5-HT1ASerotonin5-HT1A receptoranticonvulsantcannabidiol (CBD)cannabinoidsdelta-9 tetrahydrocannabinol (Δ9-THC)drug resistant epilepsyelectrophysiologyserotonin

Identifiers

PMID38534310
PMCPMC10969448
OpenAlexW4392550068

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.