Evidence map›Paper›PMID 38534686›Full record

ReviewAntibiotics (Basel, Switzerland)2024

Antimicrobial Properties of Colostrum and Milk.

Furkan Eker, Emir Akdaşçi, Hatice Duman, Yalçın Mert Yalçıntaş, Ahmet Alperen Canbolat, Arda Erkan Kalkan, Sercan Karav, Dunja Šamec

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
14.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Human colostrum as a probiotic reservoir: a genomic insights into potential probiotic traits.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Osteopontin: Its Properties, Recent Studies, and Potential Applications.International journal of molecular sciences · 2025
    Review
  14. Lactoperoxidase: Properties, Functions, and Potential Applications.International journal of molecular sciences · 2025
    Review
  15. Article
  16. Lactoferrin: Properties and Potential Uses in the Food Industry.International journal of molecular sciences · 2025
    Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Furkan EkerDepartment of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17000, Turkey.
Emir AkdaşçiDepartment of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17000, Turkey.ORCID 0009-0009-5996-6567
Hatice DumanDepartment of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17000, Turkey.
Yalçın Mert YalçıntaşDepartment of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17000, Turkey.ORCID 0009-0008-0447-1076
Ahmet Alperen CanbolatDepartment of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17000, Turkey.
Arda Erkan KalkanDepartment of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17000, Turkey.ORCID 0009-0003-6141-862X
Sercan KaravDepartment of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17000, Turkey.
Dunja ŠamecDepartment of Food Technology, University North, Trg Dr. Žarka Dolinara 1, 48000 Koprivnica, Croatia.ORCID 0000-0002-0600-6847
Çanakkale Onsekiz Mart Üniversitesi · TRUniversity North · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing number of antibiotic resistance genes is putting a strain on the ecosystem and harming human health. In addition, consumers have developed a cautious attitude towards chemical preservatives. Colostrum and milk are excellent sources of antibacterial components that help to strengthen the immunity of the offspring and accelerate the maturation of the immune system. It is possible to study these important defenses of milk and colostrum, such as lactoferrin, lysozyme, immunoglobulins, oligosaccharides, etc., as biotherapeutic agents for the prevention and treatment of numerous infections caused by microbes. Each of these components has different mechanisms and interactions in various places. The compound's mechanisms of action determine where the antibacterial activity appears. The activation of the antibacterial activity of milk and colostrum compounds can start in the infant's mouth during lactation and continue in the gastrointestinal regions. These antibacterial properties possess potential for therapeutic uses. In order to discover new perspectives and methods for the treatment of bacterial infections, additional investigations of the mechanisms of action and potential complexes are required.

Indexed as

antibacterial activitybioactive componentscolostrumimmunitymilk

Identifiers

PMID38534686
PMCPMC10967647
OpenAlexW4392662528

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.