Evidence map›Paper›PMID 38534825›Full record

ArticleBiomimetics (Basel, Switzerland)2024

Physically and Chemically Crosslinked Hyaluronic Acid-Based Hydrogels Differentially Promote Axonal Outgrowth from Neural Tissue Cultures.

Andrej Bajic, Brittmarie Andersson, Alexander Ossinger, Shima Tavakoli, Oommen P Varghese, Nikos Schizas

Open access · goldAbstract read
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Hydrogel-based neural engineering for skin wound healing.Frontiers in cell and developmental biology · 2026
    Review
  2. Review
  3. Hyaluronic Acid and Its Synthases-Current Knowledge.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andrej BajicDepartment of Surgical Sciences, Section of Orthopedics, The OrthoLab, Uppsala University, 75185 Uppsala, Sweden.
Brittmarie AnderssonDepartment of Surgical Sciences, Section of Orthopedics, The OrthoLab, Uppsala University, 75185 Uppsala, Sweden.
Alexander OssingerDepartment of Surgical Sciences, Section of Orthopedics, The OrthoLab, Uppsala University, 75185 Uppsala, Sweden.
Shima TavakoliTranslational Chemical Biology Laboratory, Division of Macromolecular Chemistry, Department of Chemistry-Ångstrom Laboratory, Uppsala University, 75237 Uppsala, Sweden.
Oommen P VargheseTranslational Chemical Biology Laboratory, Division of Macromolecular Chemistry, Department of Chemistry-Ångstrom Laboratory, Uppsala University, 75237 Uppsala, Sweden.ORCID 0000-0001-8872-9928
Nikos SchizasDepartment of Surgical Sciences, Section of Orthopedics, The OrthoLab, Uppsala University, 75185 Uppsala, Sweden.ORCID 0009-0001-8880-8463
Uppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our aim was to investigate axonal outgrowth from different tissue models on soft biomaterials based on hyaluronic acid (HA). We hypothesized that HA-based hydrogels differentially promote axonal outgrowth from different neural tissues. Spinal cord sliced cultures (SCSCs) and dorsal root ganglion cultures (DRGCs) were maintained on a collagen gel, a physically crosslinked HA-based hydrogel (Healon 5

Indexed as

axonal outgrowthdorsal root ganglion cultureHA-based hydrogelneuroprotectionspinal cord slice culture

Identifiers

PMID38534825
PMCPMC10968613
OpenAlexW4392163701

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.