Evidence map›Paper›PMID 38534972›Full record

ReviewDiseases (Basel, Switzerland)2024

Pediatric Hemangiomas in the Female Genital Tract: A Literature Review.

Lucia Merlino, Agnese Immacolata Volpicelli, Franco Anglana, Giulia D'Ovidio, Mattia Dominoni, Marianna Francesca Pasquali, Barbara Gardella, Paolo Inghirami, Pietro Lippa, Roberto Senatori

Open access · goldAbstract readReview
In one paragraph

Review in Diseases (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Bilateral large perilabial/perineal acquired kissing hemangiomas.Wiener medizinische Wochenschrift (1946) · 2026
    Article
  2. Article
  3. Vulvar Hemangioma: A Review.Diagnostics (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lucia MerlinoDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-4281-8308
Agnese Immacolata VolpicelliDepartment of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Franco AnglanaVulvar Pathology Study Center, 00161 Roma, Italy.
Giulia D'OvidioDepartment of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-7669-5430
Mattia DominoniDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-6322-607X
Marianna Francesca PasqualiDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-3744-7888
Barbara GardellaDepartment of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-0812-8995
Paolo InghiramiVulvar Pathology Study Center, 00161 Roma, Italy.
Pietro LippaVulvar Pathology Study Center, 00161 Roma, Italy.
Roberto SenatoriVulvar Pathology Study Center, 00161 Roma, Italy.
Sapienza University of Rome · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHemangiomas are aberrant proliferations of blood vessels and the most frequent benign pediatric soft tissue tumors. Although they are common, genital localization is rare. This study aimed to assist doctors in the diagnosis, management, and treatment of pediatric vulvovaginal hemangiomas by conducting a review of the literature.

methodsWe conducted a literature review including papers published between August 2009 and May 2023.

resultsWhile most hemangiomas are usually indolent and resolve with time, in some cases, especially cervicovaginal and uterine ones, they might present with severe symptoms like heavy bleeding and need further instrumental investigation for diagnosis, like CT or MRI. As for the treatment, many options are available, with medical therapy or expectant management being the first choice.

conclusionsVulvovaginal pediatric hemangiomas are rare and require more research on how to detect and manage these lesions, especially the symptomatic and the psychologically impacting ones. For the time being, treatment should be personalized based on the patient's situation and clinician's expertise.

Indexed as

hemangioma of lower genital tractpediatric hemangiomavaginal hemangiomavulvar hemangioma

Identifiers

PMID38534972
PMCPMC10969121
OpenAlexW4392231999

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.