Evidence map›Paper›PMID 38535388›Full record

ArticleInsects2024

RNAi-Mediated Silencing of

Anastasia N Naumenko, Megan L Fritz

Open access · goldAbstract read
In one paragraph

Article in Insects, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Anastasia N NaumenkoDepartment of Entomology, University of Maryland, College Park, MD 20742, USA.
Megan L FritzDepartment of Entomology, University of Maryland, College Park, MD 20742, USA.ORCID 0000-0003-0472-4877
University of Maryland, College Park · US

Funding

Genetic basis for host preference in Culex pipiensR01AI125622 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI FRITZ, MEGAN LINDSAY · 2019 to 2023
$2.0M
NIAID NIH HHS R01 AI125622NIH HHS R01AI125622A
6 · The paper itself

Abstract

Mosquitoes transmit a range of pathogens, causing devastating effects on human health. Population genetic control strategies have been developed and successfully used for several mosquito species. The most important step in identifying potential targets for mosquito control is the understanding of gene function. RNA interference (RNAi) is a powerful tool for gene silencing which has been widely used to study gene function in insects via knockdown of expression. The success of RNAi in insects depends on the efficient delivery of dsRNA into the cells, with microinjections being the most commonly used to study mosquito gene function. However, microinjections in the pupal stage lead to significant mortality in

Indexed as

Culex pipienslaccase 2RNAi

Identifiers

PMID38535388
PMCPMC10971320
OpenAlexW4392817110

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.