Evidence mapPaperPMID 38535491Full record

ArticleJournal of xenobiotics2023

The Potential for Genotoxicity, Mutagenicity and Endocrine Disruption in Triclosan and Triclocarban Assessed through a Combination of In Vitro Methods.

Jan Chrz, Markéta Dvořáková, Kristina Kejlová, Danuše Očadlíková, Lada Svobodová, Lukáš Malina, Barbora Hošíková, Dagmar Jírová, Hana Bendová, Hana Kolářová

Open access · goldAbstract read
In one paragraph

Article in Journal of xenobiotics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jan ChrzCentre of Toxicology and Health Safety, National Institute of Public Health, Šrobárova 49/48, 100 00 Prague, Czech Republic.
Markéta DvořákováCentre of Toxicology and Health Safety, National Institute of Public Health, Šrobárova 49/48, 100 00 Prague, Czech Republic.
Kristina KejlováCentre of Toxicology and Health Safety, National Institute of Public Health, Šrobárova 49/48, 100 00 Prague, Czech Republic.
Danuše OčadlíkováCentre of Toxicology and Health Safety, National Institute of Public Health, Šrobárova 49/48, 100 00 Prague, Czech Republic.
Lada SvobodováCentre of Toxicology and Health Safety, National Institute of Public Health, Šrobárova 49/48, 100 00 Prague, Czech Republic.
Lukáš MalinaDepartment of Medical Biophysics, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University in Olomouc, 779 00 Olomouc, Czech Republic.ORCID 0000-0001-5734-5921
Barbora HošíkováDepartment of Medical Biophysics, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University in Olomouc, 779 00 Olomouc, Czech Republic.
Dagmar JírováCentre of Toxicology and Health Safety, National Institute of Public Health, Šrobárova 49/48, 100 00 Prague, Czech Republic.
Hana BendováCentre of Toxicology and Health Safety, National Institute of Public Health, Šrobárova 49/48, 100 00 Prague, Czech Republic.
Hana KolářováDepartment of Medical Biophysics, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University in Olomouc, 779 00 Olomouc, Czech Republic.
National Institute of Public Health · CZInstitute of Molecular and Translational Medicine · CZ

Funding

Ministry of Education, Youith and Sport of the Czech Republic CZ.02.1.01/0.0/0.0/16_019/0000860Ministry of Health Czech Republic IN: 75010330
6 · The paper itself

Abstract

Triclosan and Triclocarban, preservatives widely used in cosmetics and other consumer products, underwent evaluation using a battery of new-approach methodologies in vitro (NAMs). Specifically, the Microplate Ames Test (MPF™ Test, Xenometrix, Allschwil, Switzerland) was employed to assess mutagenicity, the Comet assay in vitro on the HaCat cell line and the Mammalian Chromosome Aberration Test were utilized to evaluate genotoxicity, and the XenoScreen

Indexed as

Ames testchromosome aberrationsComet assayendocrine disruptiongenotoxicity/mutagenicitypreservatives

Identifiers

PMID38535491
PMCPMC10971739
OpenAlexW4390059860

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.