Evidence map›Paper›PMID 38535494›Full record

ArticleJournal of xenobiotics2024

Xenobiotics Triggering Acute Intermittent Porphyria and Their Effect on Mouse Brain Respiratory Complexes.

Johanna Romina Zuccoli, María Del Carmen Martínez, Pablo Vallecorsa, Ana María Buzaleh

Open access · goldAbstract read
In one paragraph

Article in Journal of xenobiotics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Johanna Romina ZuccoliResearch Center on Porphyrins and Porphyrias (CIPYP)-UBA-CONICET, Hospital of Clinics José de San Martín, Buenos Aires 1120, Argentina.ORCID 0000-0002-8463-307X
María Del Carmen MartínezResearch Center on Porphyrins and Porphyrias (CIPYP)-UBA-CONICET, Hospital of Clinics José de San Martín, Buenos Aires 1120, Argentina.
Pablo VallecorsaNational Atomic Energy Commission (CNEA), Buenos Aires 1429, Argentina.ORCID 0000-0001-7419-7078
Ana María BuzalehResearch Center on Porphyrins and Porphyrias (CIPYP)-UBA-CONICET, Hospital of Clinics José de San Martín, Buenos Aires 1120, Argentina.
Consejo Nacional de Investigaciones Científicas y Técnicas · ARComisión Nacional de Energía Atómica · AR

Funding

Consejo Nacional de Investigaciones Científicas y Técnicas PIP 11220130100557COUniversity of Buenos Aires UBACYT 2014-2017, 01/Q839University of Buenos Aires UBACYT 2018, 20020170100609BA
6 · The paper itself

Abstract

Heme enzyme dysfunction causes a group of diseases called porphyrias. Particularly, a decrease in porphobilinogen deaminase, involved in the third step of heme biosynthesis, leads to acute intermittent porphyria (AIP). Considering our previous works demonstrating the multiplicity of brain metabolisms affected by porphyrinogenic agents, this study aimed to elucidate whether they cause any alteration on the mitochondrial respiratory chain. The activities of respiratory chain complexes (I to IV) were measured in encephalon mitochondria of

Indexed as

5-aminolevulinic acidacute intermittent porphyriaisofluranemitochondriaporphyrinogenic agentsrespiratory chain complexessevoflurane

Identifiers

PMID38535494
PMCPMC10971141
OpenAlexW4392198265

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.