Evidence map›Paper›PMID 38535542›Full record

ArticlePathogens (Basel, Switzerland)2024

In Situ versus Systemic Immune Response in the Pathogenesis of Cutaneous Leishmaniasis.

Augusto M Carvalho, Rúbia S Costa, Alexsandro Lago, Olívia Bacellar, Daniel P Beiting, Phillip Scott, Lucas P Carvalho, Edgar M Carvalho

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Annexin A1 downregulatesFrontiers in immunology · 2025
    Article
  4. ThePathogens (Basel, Switzerland) · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Augusto M CarvalhoGonçalo Moniz Institute (IGM), Fiocruz, Salvador 40296-710, BA, Brazil.
Rúbia S CostaGonçalo Moniz Institute (IGM), Fiocruz, Salvador 40296-710, BA, Brazil.
Alexsandro LagoImmunology Service, Professor Edgard Santos University Hospital Complex, Federal University of Bahia, Salvador 40110-160, BA, Brazil.
Olívia BacellarImmunology Service, Professor Edgard Santos University Hospital Complex, Federal University of Bahia, Salvador 40110-160, BA, Brazil.ORCID 0000-0002-9759-3396
Daniel P BeitingDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-4539, USA.
Phillip ScottDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-4539, USA.
Lucas P CarvalhoGonçalo Moniz Institute (IGM), Fiocruz, Salvador 40296-710, BA, Brazil.ORCID 0000-0001-5033-1666
Edgar M CarvalhoGonçalo Moniz Institute (IGM), Fiocruz, Salvador 40296-710, BA, Brazil.ORCID 0000-0002-2697-8002
Universidade Federal da Bahia · BRUniversity of Pennsylvania · US

Funding

Host and parasite factors promoting disease and treatment failure in Leishmania braziliensis patientsR01AI149456 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI CARVALHO, LUCAS P, SCOTT, PHILLIP · 2020 to 2023
$626k
NIAID NIH HHS R01 AI149456NIH HHS RO1-A1-149456
6 · The paper itself

Abstract

The role of the immune response in the pathogenesis of cutaneous leishmaniasis (CL) due to

Indexed as

CytokinesLeishmania braziliensisLeishmaniasis, CutaneousLeukocytes, MononuclearAdolescentAdultAgedBiopsyFemaleGranzymesHumansInterferon-gammaMaleMiddle AgedYoung AdultCytokinesGranzymesInterferon-gammacutaneous leishmaniasisgranzyme BIL-17IL-1βimmune responseimmunopathologyLeishmania braziliensis

Identifiers

PMID38535542
PMCPMC10975199
OpenAlexW4392096677

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.