Evidence map›Paper›PMID 38535834›Full record

ArticleVeterinary sciences2024

Hepatic Gene Expression of Angiogenic and Regeneration Markers in Cats with Congenital Portosystemic Shunts (CPSS).

Michael S Tivers, Samantha M Mirczuk, Abigail Charlesworth, Lauren Wood, Emi N Barker, Victoria J Lipscomb, Robert C Fowkes

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Michael S TiversParagon Veterinary Referrals, Paragon Business Village, Red Hall Cres, Wakefield WF1 2DF, UK.ORCID 0000-0001-7047-9334
Samantha M MirczukEndocrine Signalling Group, Comparative Biomedical Sciences, Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK.
Abigail CharlesworthEndocrine Signalling Group, Comparative Biomedical Sciences, Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK.
Lauren WoodEndocrine Signalling Group, Comparative Biomedical Sciences, Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK.
Emi N BarkerLangford Vets, University of Bristol, Langford BS40 5DU, UK.ORCID 0000-0001-6293-6662
Victoria J LipscombClinical Sciences & Services, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL10 8TY, UK.ORCID 0000-0001-8427-5885
Robert C FowkesEndocrine Signalling Group, Comparative Biomedical Sciences, Royal Veterinary College, University of London, Royal College Street, London NW1 0TU, UK.ORCID 0000-0002-2222-2056
University of London · GBUniversity of Bristol · GBUniversity of Hertfordshire · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital portosystemic shunts (CPSS) are vascular anomalies resulting in liver hypoplasia and hepatic insufficiency. Cats with CPSS typically show signs of hepatic encephalopathy associated with increased ammonia, inflammatory cytokines, and oxidative stress. Surgical attenuation of the CPSS results in improved liver function, resolution of clinical signs, and increased portal blood flow. Hepatic gene expression has not previously been investigated in cats with CPSS. Here, we compared the hepatic expression of genes involved in the urea cycle (

Indexed as

gene expressionhepatic encephalopathyliver disease

Identifiers

PMID38535834
PMCPMC10974408
OpenAlexW4392156357

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.