ArticleToxics2024
Long-Term Environmental Methylmercury Exposure Is Associated with Peripheral Neuropathy and Cognitive Impairment among an Amazon Indigenous Population.
Article in Toxics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Influence of theInternational journal of environmental research and public health · 2026Article
- Mining and malaria in the Brazilian Amazon and in the Yanomami indigenous land.PLoS neglected tropical diseases · 2025Article
- A Brazilian Minamata disease? Neurologists must be aware of mercury exposure and intoxication.Arquivos de neuro-psiquiatria · 2025Review
- Epidemiological surveillance in congenital anomalies and rare diseases in Brazil: present situation and future challenges.Journal of community genetics · 2025Review
- Mercury Exposure and Health Effects in Indigenous People from the Brazilian Amazon-Literature-Scoping Review.International journal of environmental research and public health · 2025Article
- A cross-sectional study assessing mercury exposure and poisoning among workers in informal gold mines in French Guiana.BMJ open · 2025Article
- Burden of Disease Attributed to Prenatal Methylmercury Exposure in the Yanomami Indigenous Land.Toxics · 2025Article
- Mercury Contamination and Co-exposures in the Amazon Basin: At the Center of the Planetary Environmental Crisis.Annals of global health · 2025Review
- Mercury exposure leading to functional vitamin B12 deficiency and subacute combined degeneration: a case report and literature review.Frontiers in toxicology · 2025Article
- Single and joint exposure of Pb, Cd, Hg, Se, Cu, and Zn were associated with cognitive function of older adults.Scientific reports · 2024Article
- TheToxics · 2024Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
Widespread contamination of the Amazon basin with mercury has been reported to occur since at least the mid-80s due to heavy gold mining activity. Although initial studies have indicated that this may lead to deleterious neurological consequences to the indigenous populations living in the region, further research is needed to better characterize the neurological burden of such long-term exposure. With this aim, a cross-sectional exploratory study has been conducted with the Yanomami indigenous population residing in a northern Amazon region. All participants underwent a structured interview; detailed neurological examination, including assessment for cognitive, motor, coordination, and sensory functions; and laboratorial testing for serum hemoglobin, blood glucose, and methylmercury levels in hair samples. This study enrolled 154 individuals of 30.9 ± 16.8 years of age, of which 56.1% were female. Mean methylmercury levels in hair were 3.9 ± 1.7 µg/g. Methylmercury levels in hair > 6.0 µg/g were found in 10.3%. Among participants with hair methylmercury levels ≥ 6.0 μg/g, the prevalences of peripheral neuropathy and reduced cognitive performance were, respectively, 78.8% (95%CI 15-177%,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.