Evidence map›Paper›PMID 38536870›Full record

ArticleJournal of the American Chemical Society2024

Synthesis of Borylated Carbocycles by [2 + 2]-Cycloadditions and Photo-Ene Reactions.

Jarett M Posz, Neetu Sharma, Paige A Royalty, Yanyao Liu, Christophe Salome, Thomas C Fessard, M Kevin Brown

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Reenvisioning the De Mayo Reaction: A Boron-Enabled Cycloaddition Approach.Angewandte Chemie (International ed. in English) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Access to allyl-Chemical science · 2026
    Article
  8. Article
  9. Fused 3D boron heterocyclesChemical science · 2026
    Article
  10. Boron-Enabled Stereoselective Synthesis of Polysubstituted Housanes.Journal of the American Chemical Society · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Facile Synthesis of Housanes by an Unexpected Strategy.Journal of the American Chemical Society · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jarett M PoszDepartment of Chemistry, Indiana University, 800 E. Kirkwood Avenue, Bloomington, Indiana 47405, United States.ORCID 0000-0001-6023-7032
Neetu SharmaDepartment of Chemistry, Indiana University, 800 E. Kirkwood Avenue, Bloomington, Indiana 47405, United States.
Paige A RoyaltyDepartment of Chemistry, Indiana University, 800 E. Kirkwood Avenue, Bloomington, Indiana 47405, United States.
Yanyao LiuDepartment of Chemistry, Indiana University, 800 E. Kirkwood Avenue, Bloomington, Indiana 47405, United States.
Christophe SalomeSpiroChem AG, Rosental Area, WRO-1047-3, Mattenstrasse 22, Basel 4058, Switzerland.ORCID 0000-0001-9668-8134
Thomas C FessardSpiroChem AG, Rosental Area, WRO-1047-3, Mattenstrasse 22, Basel 4058, Switzerland.
M Kevin BrownDepartment of Chemistry, Indiana University, 800 E. Kirkwood Avenue, Bloomington, Indiana 47405, United States.ORCID 0000-0002-4993-0917

Funding

Methods and Strategies for Chemical SynthesisR35GM131755 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Michael Kevin Brown · 2019 to 2026
$4.0M
NIGMS NIH HHS R35 GM131755
6 · The paper itself

Abstract

Saturated bicyclic compounds make up a valuable class of building blocks in the development of agrochemicals and pharmaceuticals. Here, we present the synthesis of borylated bicyclo[2.1.1]hexanes via crossed [2 + 2]-cycloaddition. Due to the presence of the C-B bond, a variety of structures can be easily prepared that are not accessible by other methods. Moreover, a rare photo-ene reaction is also disclosed, allowing for the diastereoselective synthesis of trisubstituted borylated cyclopentanes.

Identifiers

PMID38536870
PMCPMC11041674

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.