Evidence map›Paper›PMID 38539193›Full record

ReviewMicrobial cell factories2024

Non-ribosomal peptide synthetase (NRPS)-encoding products and their biosynthetic logics in Fusarium.

Ziwei Huang, Wangjie Zhu, Yifan Bai, Xuelian Bai, Huawei Zhang

Open access · goldAbstract readReview
In one paragraph

Review in Microbial cell factories, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Recent Updates on the Secondary Metabolites fromJournal of fungi (Basel, Switzerland) · 2024
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ziwei HuangSchool of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, 310014, China.
Wangjie ZhuSchool of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, 310014, China.
Yifan BaiSchool of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, 310014, China.
Xuelian BaiCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, 310036, China.
Huawei ZhangSchool of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, 310014, China. hwzhang@zjut.edu.cn.
Zhejiang University of Technology · CNHangzhou Normal University · CN

Funding

National Key Research and Development Program of China Stem Cell and Translational Research 2018YFC0311004National Key Research and Development Program of China Stem Cell and Translational Research 2022YFC2804203National Natural Science Foundation of China 41776139
6 · The paper itself

Abstract

Fungal non-ribosomal peptide synthetase (NRPS)-encoding products play a paramount role in new drug discovery. Fusarium, one of the most common filamentous fungi, is well-known for its biosynthetic potential of NRPS-type compounds with diverse structural motifs and various biological properties. With the continuous improvement and extensive application of bioinformatic tools (e.g., anti-SMASH, NCBI, UniProt), more and more biosynthetic gene clusters (BGCs) of secondary metabolites (SMs) have been identified in Fusarium strains. However, the biosynthetic logics of these SMs have not yet been well investigated till now. With the aim to increase our knowledge of the biosynthetic logics of NPRS-encoding products in Fusarium, this review firstly provides an overview of research advances in elucidating their biosynthetic pathways.

Indexed as

FusariumBiosynthetic PathwaysComputational BiologyFungiMultigene FamilyPeptide Synthasesnon-ribosomal peptide synthasePeptide SynthasesBiosynthetic gene clusterBiosynthetic pathwayFusariumNon-ribosomal peptide synthetase-encoding productSecondary metabolite

Identifiers

PMID38539193
PMCPMC10967133
OpenAlexW4393227664

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.