Evidence map›Paper›PMID 38540897›Full record

ReviewFoods (Basel, Switzerland)2024

Milk Bioactive Compounds and Gut Microbiota Modulation: The Role of Whey Proteins and Milk Oligosaccharides.

Valentina Gallo, Alyexandra Arienzo, Federica Tomassetti, Giovanni Antonini

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  13. Frontiers in microbiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Valentina GalloDepartment of Science, Roma Tre University, Viale Guglielmo Marconi 446, 00146 Rome, Italy.
Alyexandra ArienzoNational Institute of Biostructures and Biosystems (INBB), Viale delle Medaglie d'Oro 305, 00136 Rome, Italy.ORCID 0000-0003-3071-4285
Federica TomassettiDepartment of Science, Roma Tre University, Viale Guglielmo Marconi 446, 00146 Rome, Italy.
Giovanni AntoniniDepartment of Science, Roma Tre University, Viale Guglielmo Marconi 446, 00146 Rome, Italy.ORCID 0000-0002-2115-8961

Funding

National Funding for Centers of Excellence (Science Department 2023-2027, Roma Tre University, MIUR, Articolo 1, Commi 314-337, Legge 232/2016) n.a.Next Generation EU PNRR Rome Technopole (ECS_00000024), by MUR, PNRR, Missione 4 Componente 2, "Dalla ricerca all'impresa, Investimento 1.4". ECS_00000024
6 · The paper itself

Abstract

A strong correlation between the occurrence of various pathological conditions and intestinal dysbiosis is supported by a range of strong evidence. Vice versa, many pathologies have been shown, in turn, to be responsible for alterations in the gut microbiota, a condition that can worsen illness outcomes and response to therapies. For these reasons, great efforts have been made, and studies are still ongoing, to elucidate the mechanisms underlying gut microbiota alterations and to search for pharmacologic or other strategies that can effectively restore the gut microbiota. In this narrative review, we examined the most significant literature on the role of some milk bioactive compounds, such as milk oligosaccharides and whey proteins, in modulating the composition of the gut microbiota and the underlying mechanisms of action, with the aim of investigating the impact of the microbiota changes mediated by these milk bioactive molecules on human health, and their potential use as therapeutics to treat or adjuvate the treatment of gut dysbiosis and associated pathologies.

Indexed as

glycomacropeptidegut microbiotalactalbuminlactoferrinlactoperoxidaselysozymemilk oligosaccharidesprebioticsprobioticswhey proteins

Identifiers

PMID38540897
PMCPMC10969594

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.