Evidence map›Paper›PMID 38542307›Full record

ReviewInternational journal of molecular sciences2024

Enhancing Clinical Utility: Utilization of International Standards and Guidelines for Metagenomic Sequencing in Infectious Disease Diagnosis.

Chau-Ming Kan, Hin Fung Tsang, Xiao Meng Pei, Simon Siu Man Ng, Aldrin Kay-Yuen Yim, Allen Chi-Shing Yu, Sze Chuen Cesar Wong

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Cavitary nodule caused byFrontiers in medicine · 2026
    Article
  7. Review
  8. Article
  9. Case Report: Beyond commensal:Frontiers in pediatrics · 2026
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Liquid Biopsy in the Clinical Management of Cancers.International journal of molecular sciences · 2024
    Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chau-Ming KanDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Hin Fung TsangDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Xiao Meng PeiDepartment of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China.
Simon Siu Man NgDepartment of Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Aldrin Kay-Yuen YimCodex Genetics Limited, Shatin, Hong Kong, China.
Allen Chi-Shing YuCodex Genetics Limited, Shatin, Hong Kong, China.ORCID 0000-0002-9568-8316
Sze Chuen Cesar WongDepartment of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China.

Funding

Lim Peng Suan Charitable Trust Research Grant P0046023
6 · The paper itself

Abstract

Metagenomic sequencing has emerged as a transformative tool in infectious disease diagnosis, offering a comprehensive and unbiased approach to pathogen detection. Leveraging international standards and guidelines is essential for ensuring the quality and reliability of metagenomic sequencing in clinical practice. This review explores the implications of international standards and guidelines for the application of metagenomic sequencing in infectious disease diagnosis. By adhering to established standards, such as those outlined by regulatory bodies and expert consensus, healthcare providers can enhance the accuracy and clinical utility of metagenomic sequencing. The integration of international standards and guidelines into metagenomic sequencing workflows can streamline diagnostic processes, improve pathogen identification, and optimize patient care. Strategies in implementing these standards for infectious disease diagnosis using metagenomic sequencing are discussed, highlighting the importance of standardized approaches in advancing precision infectious disease diagnosis initiatives.

Indexed as

Communicable DiseasesHigh-Throughput Nucleotide SequencingHumansMetagenomeMetagenomicsReference StandardsReproducibility of Resultsimplementation and validationinfectious disease diagnosisISO15189ISO20397ISO24420metagenomics sequencingnext generation sequencing

Identifiers

PMID38542307
PMCPMC10970082

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.