Evidence map›Paper›PMID 38542439›Full record

ArticleInternational journal of molecular sciences2024

Long Non-Coding RNA-Cardiac-Inducing RNA 6 Mediates Repair of Infarcted Hearts by Inducing Mesenchymal Stem Cell Differentiation into Cardiogenic Cells through Cyclin-Dependent Kinase 1.

Xiaotian Cui, Hui Dong, Shenghe Luo, Bingqi Zhuang, Yansheng Li, Chongning Zhong, Yuting Ma, Lan Hong

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  3. Review
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiaotian CuiDepartment of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji 133002, China.
Hui DongDepartment of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji 133002, China.
Shenghe LuoDepartment of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji 133002, China.
Bingqi ZhuangDepartment of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji 133002, China.
Yansheng LiDepartment of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji 133002, China.
Chongning ZhongDepartment of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji 133002, China.
Yuting MaDepartment of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji 133002, China.
Lan HongDepartment of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji 133002, China.ORCID 0000-0003-1010-6039
Yanbian University · CN

Funding

A Key projects of science and technology development plan of Jilin province 20210204152YYNational Natural Science Foundation of China 82360065
6 · The paper itself

Abstract

This study aims to investigate the induction effect of LncRNA-CIR6 on MSC differentiation into cardiogenic cells in vitro and in vivo. In addition to pretreatment with Ro-3306 (a CDK1 inhibitor), LncRNA-CIR6 was transfected into BMSCs and hUCMSCs using jetPRIME. LncRNA-CIR6 was further transfected into the hearts of C57BL/6 mice via 100 μL of AAV9-cTnT-LncRNA-CIR6-ZsGreen intravenous injection. After three weeks of transfection followed by AMI surgery, hUCMSCs (5 × 10

Indexed as

Mesenchymal Stem CellsMesenchymal Stem Cell TransplantationMyocardial InfarctionQuinolinesRNA, Long NoncodingThiazolesAnimalsCDC2 Protein KinaseCell DifferentiationMiceMice, Inbred C57BLMyocytes, CardiacCDC2 Protein KinaseCdk1 protein, mouseQuinolinesRNA, Long NoncodingRO 3306ThiazolesBMSCsCDK1hUMSCsLncRNA-CIR6myocardial infarction

Identifiers

PMID38542439
PMCPMC10971150
OpenAlexW4393007206

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.