Evidence map›Paper›PMID 38542812›Full record

SynthesisNutrients2024

The Relationship between Post-Traumatic Stress Disorder Due to Brain Injury and Glutamate Intake: A Systematic Review.

Benjamin F Gruenbaum, Alexander Zlotnik, Anna Oleshko, Frederic Matalon, Honore N Shiyntum, Amit Frenkel, Matthew Boyko

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. German Chamomile (International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Benjamin F GruenbaumAnesthesiology and Perioperative Medicine, Mayo Clinic, Jacksonville, FL 32224, USA.
Alexander ZlotnikAnesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, Beer Sheva 84101, Israel.
Anna OleshkoBiology and Methods of Teaching Biology, A. S. Makarenko Sumy State Pedagogical University, 40002 Sumy, Ukraine.
Frederic MatalonAnesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, Beer Sheva 84101, Israel.ORCID 0009-0007-1902-2794
Honore N ShiyntumAnesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, Beer Sheva 84101, Israel.
Amit FrenkelEmergency Medicine Recanati School for Community Health Professions, Ben-Gurion University of the Negev, Beer Sheva 84101, Israel.ORCID 0000-0002-4162-8406
Matthew BoykoAnesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, Beer Sheva 84101, Israel.ORCID 0000-0003-3116-1643
Ben-Gurion University of the Negev · ILMayo Clinic in Florida · USSumy State Pedagogical University named after A. S. Makarenko · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a growing body of evidence that suggests a connection between traumatic brain injury (TBI) and subsequent post-traumatic stress disorder (PTSD). While the exact mechanism is unknown, we hypothesize that chronic glutamate neurotoxicity may play a role. The consumption of dietary glutamate is a modifiable factor influencing glutamate levels in the blood and, therefore, in the brain. In this systematic review, we explored the relationship between dietary glutamate and the development of post-TBI PTSD. Of the 1748 articles identified, 44 met the inclusion criteria for analysis in this review. We observed that individuals from countries with diets traditionally high in glutamate had greater odds of developing PTSD after TBI (odds ratio = 15.2, 95% confidence interval 11.69 to 19.76,

Indexed as

Brain InjuriesBrain Injuries, TraumaticStress Disorders, Post-TraumaticBrainGlutamic AcidHumansGlutamic Acidblood–brain barrierdietglutamatepost-traumatic stress disordertraumatic brain injury

Identifiers

PMID38542812
PMCPMC10975349
OpenAlexW4393046505

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.