Evidence map›Paper›PMID 38543141›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

The Effects of Selected Extraction Methods and Natural Deep Eutectic Solvents on the Recovery of Active Principles from

Alyona Kaleta, Nadezhda Frolova, Anastasia Orlova, Alena Soboleva, Natalia Osmolovskaya, Elena Flisyuk, Olga Pozharitskaya, Andrej Frolov, Alexander Shikov

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 21 citations in OpenAlex.

  1. Safety of NADES Extract ofMolecules (Basel, Switzerland) · 2025
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Alyona KaletaDepartment of Technology of Pharmaceutical Formulations, St. Petersburg State Chemical Pharmaceutical University, 197376 Saint-Petersburg, Russia.ORCID 0000-0002-0979-2281
Nadezhda FrolovaLaboratory of Analytical Biochemistry and Biotechnology, K.A. Timiryazev Institute of Plant Physiology RAS, 127276 Moscow, Russia.ORCID 0000-0002-1895-1133
Anastasia OrlovaLaboratory of Analytical Biochemistry and Biotechnology, K.A. Timiryazev Institute of Plant Physiology RAS, 127276 Moscow, Russia.ORCID 0000-0002-7836-5785
Alena SobolevaLaboratory of Analytical Biochemistry and Biotechnology, K.A. Timiryazev Institute of Plant Physiology RAS, 127276 Moscow, Russia.ORCID 0000-0002-7318-8628
Natalia OsmolovskayaDepartment of Plant physiology and Biochemistry, St. Petersburg State University, Universitetskaya Nab. 7-9, 199034 St. Petersburg, Russia.
Elena FlisyukDepartment of Technology of Pharmaceutical Formulations, St. Petersburg State Chemical Pharmaceutical University, 197376 Saint-Petersburg, Russia.
Olga PozharitskayaResearch Group of Biochemistry and Technology of Hydrobionts of Algae and Invertebrates, Murmansk Marine Biological Institute of the Russian Academy of Sciences (MMBI RAS), 17 Vladimirskaya Str., 183010 Murmansk, Russia.ORCID 0000-0003-1061-0665
Andrej FrolovLaboratory of Analytical Biochemistry and Biotechnology, K.A. Timiryazev Institute of Plant Physiology RAS, 127276 Moscow, Russia.
Alexander ShikovDepartment of Technology of Pharmaceutical Formulations, St. Petersburg State Chemical Pharmaceutical University, 197376 Saint-Petersburg, Russia.ORCID 0000-0003-4351-0695
Timiryazev Institute of Plant Physiology · RUSaint - Petersburg State Chemical Pharmaceutical Academy · RUMurmansk Marine Biological Institute · RUSt Petersburg University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The methods and solvents employed in routine extraction protocols essentially impact the composition of the resulting extracts, i.e., the relative abundances of individual biologically active metabolites and the quality and stability of the isolates. Natural deep eutectic solvents (NADESs) represent a new class of environmentally friendly solvents, which are recognized as promising extractants alternative to conventional organic liquids. However, their relative efficiencies when applied in different extraction workflows are still poorly characterized. Therefore, here, we compare the potential of three extraction methods for the extraction of biologically active natural products from

Indexed as

Aralia elataextractionNADESnatural deep eutectic solventsnon-targeted metabolics profilingultrasound-assisted extractionvibrocavitation-assisted extraction

Identifiers

PMID38543141
PMCPMC10974460
OpenAlexW4392647093

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.