Evidence mapPaperPMID 38544365Full record

ReviewCNS neuroscience & therapeutics2024

Tracing the path of disruption:

Charles J Peper, Mitchell D Kilgore, Yinghua Jiang, Yuwen Xiu, Winna Xia, Yingjie Wang, Mengxuan Shi, Di Zhou, Aaron S Dumont, Xiaoying Wang and 1 more

Abstract readReview
In one paragraph

Review in CNS neuroscience & therapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Multi Omics Applications in Biological Systems.Current issues in molecular biology · 2024
    Review
  3. Tracing the path of disruption:CNS neuroscience & therapeutics · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Charles J PeperClinical Neuroscience Research Center, Departments of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana, USA.ORCID 0000-0002-3520-4359
Mitchell D KilgoreClinical Neuroscience Research Center, Departments of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana, USA.ORCID 0000-0003-1101-6924
Yinghua JiangClinical Neuroscience Research Center, Departments of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Yuwen XiuClinical Neuroscience Research Center, Departments of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana, USA.ORCID 0000-0002-2083-7129
Winna XiaClinical Neuroscience Research Center, Departments of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Yingjie WangClinical Neuroscience Research Center, Departments of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Mengxuan ShiClinical Neuroscience Research Center, Departments of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Di ZhouClinical Neuroscience Research Center, Departments of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Aaron S DumontClinical Neuroscience Research Center, Departments of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Xiaoying WangClinical Neuroscience Research Center, Departments of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana, USA.ORCID 0000-0003-3636-7931
Ning LiuClinical Neuroscience Research Center, Departments of Neurosurgery and Neurology, Tulane University School of Medicine, New Orleans, Louisiana, USA.ORCID 0000-0002-5632-0359

Funding

Tulane COBRE for Clinical and Translational Research in Cardiometabolic DiseasesP20GM109036 · TULANE UNIVERSITY OF LOUISIANA · 2025 to 2025
$2.2M
Role of Irg-1/itaconate in modulating secondary brain damage after traumatic brain injury in miceR01NS126503 · NINDS · TULANE UNIVERSITY OF LOUISIANA · 2024 to 2025
$815k
American Heart Association Career Development Award 23CDA1055341National Institutes of Health (NIH) 1RO1 NS126503-01A1NIGMS NIH HHS P20 GM109036NINDS NIH HHS R01 NS126503The Tulane COBRE for Clinical and Translational Research in Cardiometabolic Diseases, National Institutes of Health P20GM109036Tulane School of Medicine Pilot Fund Award
6 · The paper itself

Abstract

Cerebral metabolic dysfunction is a critical pathological hallmark observed in the aftermath of traumatic brain injury (TBI), as extensively documented in clinical investigations and experimental models. An in-depth understanding of the bioenergetic disturbances that occur following TBI promises to reveal novel therapeutic targets, paving the way for the timely development of interventions to improve patient outcomes. The

Indexed as

Brain Injuries, TraumaticAnimalsEnergy MetabolismHumansIsotopesIsotopes13C isotopebioenergeticsmetabolismtraumatic brain injury

Identifiers

PMID38544365
PMCPMC10973562

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.