Evidence map›Paper›PMID 38546887›Full record

ReviewArchives of microbiology2024

Cryosphere: a frozen home of microbes and a potential source for drug discovery.

Sahib Zada, Mohsin Khan, Zheng Su, Wasim Sajjad, Muhammad Rafiq

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Sahib Zada *Guangzhou Institute of Energy Conversion, Chinese Academy of Sciences, Guangzhou, China.
Mohsin Khan *Department of Biological Sciences, Ohio University Athens, Athens, OH, USA.
Zheng SuGuangzhou Institute of Energy Conversion, Chinese Academy of Sciences, Guangzhou, China.
Wasim SajjadState Key Laboratory of Cryospheric Science, Northwest Institute of Eco-Environment and Resources, Chinese Academy of Sciences, Lanzhou, 730000, China. wasim.sajjad71@yahoo.com.
Muhammad RafiqDepartment of Microbiology, Faculty of Life Sciences and Informatics, Balochistan University of IT, Engineering and Management Sciences, Quetta, 87650, Pakistan. mr14311@my.bristol.ac.uk.
Balochistan University of Information Technology, Engineering and Management Sciences · PKChinese Academy of Sciences · CNGuangzhou Institute of Energy Conversion · CNNorthwest Institute of Eco-Environment and Resources · CNOhio University · US

Funding

Gansu Provincial Science and Technology Program 22ZD6FA005
6 · The paper itself

Abstract

The world is concerned about the emergence of pathogens and the occurrence and spread of antibiotic resistance among pathogens. Drug development requires time to combat these issues. Consequently, drug development from natural sources is unavoidable. Cryosphere represents a gigantic source of microbes that could be the bioprospecting source of natural products with unique scaffolds as molecules or drug templates. This review focuses on the novel source of drug discovery and cryospheric environments as a potential source for microbial metabolites having potential medicinal applications. Furthermore, the problems encountered in discovering metabolites from cold-adapted microbes and their resolutions are discussed. By adopting modern practical approaches, the discovery of bioactive compounds might fulfill the demand for new drug development.

Indexed as

Biological ProductsDrug DiscoveryBioprospectingBiological ProductsAntibiotic resistanceAntimicrobial compoundsCryosphereDrug discoveryNovel microbes

Identifiers

PMID38546887
OpenAlexW4393263137

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.