Evidence map›Paper›PMID 38548784›Full record

ArticleScientific reports2024

Coumarin linked to 2-phenylbenzimidazole derivatives as potent α-glucosidase inhibitors.

Mina Sadeghi Ganjeh, Ali Mazlomifar, Ashraf Sadat Shahvelayti, Shiva Khalili Moghaddam

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mina Sadeghi GanjehDepartment of Chemistry, College of Basic Sciences, Yadegar-e-Imam Khomeini (RAH) Shahre Rey Branch, Islamic Azad University, Tehran, Iran.
Ali MazlomifarDepartment of Chemistry, College of Basic Sciences, Yadegar-e-Imam Khomeini (RAH) Shahre Rey Branch, Islamic Azad University, Tehran, Iran. mazloomifar@yahoo.com.
Ashraf Sadat ShahvelaytiDepartment of Chemistry, College of Basic Sciences, Yadegar-e-Imam Khomeini (RAH) Shahre Rey Branch, Islamic Azad University, Tehran, Iran.
Shiva Khalili MoghaddamDepartment of Biology, College of Basic Sciences, Yadegar-e-Imam Khomeini (RAH) Shahre Rey Branch, Islamic Azad University, Tehran, Iran.
Islamic Azad University, Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

α-Glucosidase inhibitors have emerged as crucial agents in the management of type 2 diabetes mellitus. In the present study, a new series of coumarin-linked 2-phenylbenzimidazole derivatives 5a-m was designed, synthesized, and evaluated as anti-α-glucosidase agents. Among these derivatives, compound 5k (IC

Indexed as

BenzimidazolesDiabetes Mellitus, Type 2Glycoside Hydrolase Inhibitorsalpha-GlucosidasesCoumarinsHumansKineticsMolecular Docking SimulationMolecular StructureStructure-Activity Relationship2-phenylbenzimidazolealpha-GlucosidasesBenzimidazolesCoumarinsGlycoside Hydrolase Inhibitors2-PhenylbenzimidazoleCoumarinMolecular modelingα-Glucosidase

Identifiers

PMID38548784
PMCPMC10978946
OpenAlexW4393257352

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.