Evidence map›Paper›PMID 38549078›Full record

ArticleBMC nephrology2024

Decreased renal function among children born to women with obstructed labour in Eastern Uganda: a cohort study.

David Mukunya, Faith Oguttu, Brendah Nambozo, Ritah Nantale, Brian Tonny Makoko, Agnes Napyo, Josephine Tumuhamye, Solomon Wani, Prossy Auma, Ketty Atim and 8 more

Open access · goldAbstract read
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In one paragraph

Article in BMC nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

David Mukunya *Department of Community and Public Health, Busitema University, Mbale, Uganda.
Faith Oguttu *Department of Community and Public Health, Busitema University, Mbale, Uganda. faithfaithoguttu@gmail.com.
Brendah NambozoDepartment of Community and Public Health, Busitema University, Mbale, Uganda.
Ritah NantaleDepartment of Obstetrics and Gynecology, Busitema University, Mbale, Uganda.
Brian Tonny MakokoDepartment of Community and Public Health, Busitema University, Mbale, Uganda.
Agnes NapyoDepartment of Community and Public Health, Busitema University, Mbale, Uganda.
Josephine TumuhamyeMakerere University Hospital, Makerere University Kampala, Kampala, Uganda.
Solomon WaniDepartment of Community and Public Health, Busitema University, Mbale, Uganda.
Prossy AumaMbale Regional Referral Hospital, Mbale, Uganda.
Ketty AtimMbale Regional Referral Hospital, Mbale, Uganda.
Doreck NahuriraDepartment of Obstetrics and Gynecology, Busitema University, Mbale, Uganda.
Dedan OkelloDepartment of Paediatrics and Child Health, Busitema University, Mbale, Uganda.
Joan WamulugwaMbale Regional Referral Hospital, Mbale, Uganda.
Lawrence SsegawaDepartment of Research, Sanyu Africa Research Institute, Mbale, Uganda.
Julius WandabwaDepartment of Obstetrics and Gynecology, Busitema University, Mbale, Uganda.
Sarah KiguliDepartment of Paediatrics and Child Health, Makerere University, Kampala, Uganda.
Martin ChebetDepartment of Paediatrics and Child Health, Busitema University, Mbale, Uganda.
Milton W MusabaDepartment of Obstetrics and Gynecology, Busitema University, Mbale, Uganda.
Busitema University · UGMbale Hospital · UGMakerere University · UGSanyu Africa Research Institute · UG

Funding

Busitema University BURIF-round-2-minute2/3/2021National Institutes of Health, U.S. Department of State’s Office
6 · The paper itself

Abstract

backgroundOver two million children and adolescents suffer from chronic kidney disease globally. Early childhood insults such as birth asphyxia could be risk factors for chronic kidney disease in later life. Our study aimed to assess renal function among children aged two to four years, born to women with obstructed labour.

methodsWe followed up 144 children aged two to four years, born to women with obstructed labor at Mbale regional referral hospital in Eastern Uganda. We used serum creatinine to calculate estimated glomerular filtration rate (eGFR) using the Schwartz formula. We defined decreased renal function as eGFR less than 90 ml/min/1.73m

resultsThe mean age of the children was 2.8 years, standard deviation (SD) of 0.4 years. Majority of the children were male (96/144: 66.7%). The mean umbilical lactate level at birth among the study participants was 8.9 mmol/L with a standard deviation (SD) of 5.0. eGFR of the children ranged from 55 to 163 ml/min/1.73m

conclusionWe observed a high incidence of reduced renal function among children born to women with obstructed labour. We recommend routine follow up of children born to women with obstructed labour and add our voices to those calling for improved intra-partum and peripartum care.

Indexed as

Renal Insufficiency, ChronicAdolescentChildChild, PreschoolCohort StudiesFemaleFollow-Up StudiesGlomerular Filtration RateHumansInfant, NewbornKidneyMaleUgandaChildreneGFRObstructed labourRenal functionUganda

Identifiers

PMID38549078
PMCPMC10976667
OpenAlexW4393268556

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.